N-(5-methylimidazol-4-yl)methyl-N,N,N- trimethyl ammonium iodide with cysteamine in a polar organic solvent (preferably methanol, ethanol, etc.) in a basic condition with e.g. alkali metal alkoxide, caustic alkali, etc. at 0-35 deg.C for 5min-3hr. USE:Intermediate for the preparation...
In this work, D-(–)-α-phenylglycine (APG)-functionalized magnetic nanocatalyst (Fe3O4@SiO2@PTS-APG) was designed and successfully prepared in order to implement the principles of green chemistry for the synthesis of polyhydroquinoline (PHQ) and 1,4-dihydropyridine (1,4-DHP) derivatives unde...
wherein n is 0, 1, 2 or 3 and both q's are 0 or one is 0 and the other is 1 [0010] wherein R6is hydrogen or C1-3alkyl, with the general proviso that -X-Z and the R4bearing phenyl group are ortho to each other; in free acid form or in the form of a physioiogically-...
The mixture is stirred and an HCl scavenger such as imidazole is added when the halogenation is involved. Mixing of the base and the solution is very exothermic and should be carried out at a controlled rate with complete cooling. After addition of the base, the resulting mixture is allowed ...
Interaction of 2-unsubstituted imidazoleN-oxides with electron-deficient olefins: a quantum chemical analysis Reactions between the model compoundN-1,4,5-trimethyl-1H-imidazole-3-oxide and electron-deficient olefins including 2-(4-methoxybenzylidene)malononitrile, ... Yu. M. Selivantev,V. S. Mit...
The present invention is directed to a processes for the synthesis of trans isomer of 4,6-disubstituted-tetrahydro-furo, thieno, pyrrolo and cyclopenta-[3,4][1,3]dioxoles (Formula I
The present invention relates to novel compounds representated by formula (I), where R, R1, R2, R3, X, Y, m, n are as defined. The present invention relates to compounds of the gene
The invention discloses a preparation method for a 1-p-chlorphenyl-2-(4'-N, N'-dimethylamino phenyl)-4,5 diphenyl imidazole compound. According to the method, 1,2-deoxybenzoin, p-chloroaniline, N, N'-dimethylamino benzoic aldehyde, ammonium acetate and trimethylchlorosilane are placed in a ...
5- to 6-membered aromatic heterocyclic rings having 1 to 4 hetero atoms of 1 to 2 types selected from a nitrogen atom, a sulfur atom and an oxygen atom such as furan, thiophene, pyrrole, imidazole, pyrazole, thiazole, oxazole, isothiazole, isoxazole, tetrazole, pyridine, pyrazine, pyrimidine...
1. A process for the preparation of a compound of formula (I) wherein is selected from the group consisting aryl and heteroaryl; provided that the heteroaryl group does not contain a nitrogen atom; a is an integer from 1 to 3; R1 is selected from the group consisting of hydrogen, haloge...