The lowest possible dose of corticosteroids should be used to control the condition under treatment. When reduction in dosage is possible, the reduction should be gradual. Since complications of treatment with glucocorticoids are dependent on the size of the dose and the duration of treatment, a ri...
including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy); ankylosing spondylitis; acute and subacute bursitis; acute nonspecific tenosynovitis; acute gouty arthritis; posttraumatic osteoarthritis; synovitis
Dosing should be individualized based on disease and patient response: Initial dose: 5 to 60 mg orally per day Maintenance dose: Adjust or maintain initial dose until a satisfactory response is obtained; then, gradually in small decrements at appropriate intervals decrease to the lowest dose that...
both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Prednisone is a white to practically white, odorless, crystalline powder. It is very slightly soluble in water; slightly soluble in alcohol, chloroform, dioxane, and methanol. ...
dose of certain corticosteroids will produce adrenocortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenocortical suppression for 1¼ to 1½ days following a single dose)...
and starts working within an hour. You can get relief within an hour if you choose the right dose for your pain. They also have a long lasting duration. The OTCs can last up to a day. But you have to rest and take the precautionary measures for it to work longer. They can really...
Prolonged therapy with this drug causes the adrenal glands to atrophy and stop producing cortisol, so when Prednisone is discontinued after a period of prolonged therapy, the dose of Prednisone must be tapered to allow the adrenal glands time to recover. Note: this instruction presented here just...
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The lowest possible dose of corticosteroid should be used to control the condition under treatment, and when reduction in dosage is possible, the reduction should be gradual. Psychic derangements may appear when corticosteroids are used, ranging fromeuphoria, insomnia, mood swings, personality changes,...
Since complications of treatment with glucocorticoids are dependent on the size of the dose and the duration of treatment, a risk/benefit decision must be made in each individual case as to dose and duration of treatment and as to whether daily or intermittent therapy should be used. ...