必应词典为您提供prediction-of-protein-structure的释义,网络释义: 蛋白质结构预测;研究蛋白质的结构;
The prediction of protein structure, based primarily on sequence and structure homology, has become an increasingly important activity. Homology models have become more accurate and their range of applicability has increased. Progress has come, in part, from the flood of sequence and structure ...
20世纪60年代后期,Anfinsen首先发现去折叠蛋白或者说变性(denatured)蛋白质在允许重新折叠的实验条件下可以重新折叠到原来的结构,这种天然结构(native structure)对于蛋白质行使生物功能具有重要作用,大多数蛋白质只有在折叠成其天然结构的时候才能具有完全的生物活性。自从Anfinsen提出蛋白质折叠的信息隐含在蛋白质的一级结构...
Protein language models have shown significant advantages in computational biology, being able to convert protein sequences into high-dimensional representations and capture deep features, and are widely used in the prediction of protein structure and function. These models leverage advanced machine learning...
Due to the complexity of the protein structure, it can be reasonably to employ two-dimensional (2-D) wavelet de-noising rather than one-dimensional (1-D) wavelet de-noising. To illustrate the validity of 2-D wavelet denoising, it is compared with the 1-D wavelet denoising in the ...
Protein-ligand docking is an established tool in drug discovery and development to narrow down potential therapeutics for experimental testing. However, a high-quality protein structure is required and often the protein is treated as fully or partially r
ProteinNet: a standardized data set for machine learning of protein structure Follow AF2工作有: OpenFold以及对应的训练数据集OpenProteinSet RGN2 (end-to-end differentiable recurrent geometric network (RGN) 端对端的几何模型,22年发表在Nature Biotechnology) ...
蛋白质结构预测是根据蛋白质的氨基酸序列,利用计算机技术预测蛋白质三维结构的方法。Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence by using computational techniques. 根据蛋白质的氨基酸序列,利用计算机技术预测蛋白质三维结构的方法。Protei...
蛋白质结构预测(protein structure prediction) 一种生物体的基因组规定了所有构成该生物体的蛋白质,基因规定了 组成蛋白质的氨基酸序列。虽然蛋白质由氨基酸的线性序列组成,但是,它们只有折叠成特定的空间构象才能具有相应的活性和相应的生 物学功能。了解蛋白质的空间结构不仅有利于认识蛋白质的功能,也 有利于认识蛋白...
Thus,systematic study on G protein structure and functions had very important effects on new medicine producing. 对G蛋白结构与功能的系统研究是新型药剂研制与开发的基础。5) protein structure and function 蛋白质结构与功能 1. In the protein structure and function teaching of chemical and pharmaceutica...