Using a combination of phylogenetic and molecular biology techniques, it is possible to predict and 'resurrect' ancient proteins with ancestral sequence reconstruction methods and gene synthesis. One particular enzyme that has had profound implications for life on Earth is RuBisCO, the predominant enzyme...
Dynalign is initially implemented in this paper as a computational ncRNA classifier by using it to compute the ΔG°totalof an input sequence pair, then comparing that value to the mean of ΔG°totals of control sequence pairs generated specifically for that input pair. If the ΔG°totalof ...