Sutro Biopharma combines its powerful cell-free protein synthesis platform with click chemistry to develop precisely engineered bioconjugate therapeutics for oncology.
Abbas Q, Yousaf B, Amina AMU, Munir MAM, El-Naggar A, Rinklebe J, Naushad M (2020) Transformation pathways and fate of engineered nanoparticles (ENPs) in distinct interactive environmental compartments: a review. Env Int 138:105646. https://doi.org/10.1016/j.envint.2020.105646 Article CAS ...
Pressure-engineered electrophoretic deposition for gentamicin loading within osteoblast-specific cellulose nanofiber scaffolds. Mater Chem Phys. 2021;272:125018. Article CAS Google Scholar Keselowsky BG, Collard DM, García AJ. Surface chemistry modulates fibronectin conformation and directs integrin ...
By comparing PXRD patterns and FT-IR spectra, the structural consistency between the powder and the membranes of COF-Bu and COF-Ph were confirmed (Section D in the Supplementary Information). Contact angle (CA) analysis was used to study the wettability of these membranes. It was found that ...
Herbst RS, Gordon MS, Fine GD, Sosman JA, Soria J-C, Hamid O, Powderly JD, Burris HA, Mokatrin A, Kowanetz M, et al. A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors. J Clin Oncol. 2013;31:3000. Google Scholar Kim JH...
There are further provided embodiments for use of the lipid mix compositions of the invention in the preparation of a pharmaceutical for modulating T cells wherein the T cells are isolated from patients, or for T cells that have been engineered specifically to T cells or allogenic T cells.In ...
Engineered targeted peptides, such as RGD1-melittin, could be delivered intravenously to enable a more selective homing and uptake into tumor cells. Melittin could also be delivered through targeted nanoparticle approaches, such as those previously reported with “nanobees”77,78. Linking melittin ...
Mimicking Pathogenic Invasion with the Complexes of Au22(SG)18-Engineered Assemblies and Folic Acid. ACS Nano 2018, 12, 4408–4418. [Google Scholar] [CrossRef] [PubMed] [Green Version] Wu, Z.; Dong, C.; Li, Y.; Hao, H.; Zhang, H.; Lu, Z.; Yang, B. Self-assembly of Au15...
An inflammasome is a multi-protein complex that increases the production of pro-inflammatory cytokines, resulting in intense inflammation [68]. A recent study showed that the administration of genetically engineered AIEC, which lacks an enzyme required for the synthesis of propionate, resulted in a ...
The manufacturing processes of polymeric nanoparticles are relatively simple, and since polymers can be synthesized from a wide variety of monomers with different properties, engineered polymeric NPs can be produced in various shapes and sizes or with other surface properties such as porosity. This make...