The organizer is a central feature of vertebrate embryogenesis and is functionally subdivided into the head organizer that gives rise primarily to the prechordal plate and induces forebrain structures, and the trunk/tail organizer that gives rise primarily to the notochord and induces more posterior ...
Fig. 1. Removal of the prechordal plate (PrCP) induces HPE in rat embryos. Shh is expressed throughout the axial mesendoderm, notochordal and prechordal plate (A), whereas Gsc is localized to PrCP cells (B). The black bracket delineates the position of the PrCP (B). Scanning electro...