One hypothesis is that preictal vasoconstriction sur- rounding the seizure focus could actively shunts blood to the ictal focus to prepare the focus for the impending dramatic increase in neuronal activity and metabolism18. However, as shown in Fig. 3, locations with either increase (left thalamus...
The mutation was not detected in Africans from sur- rounding countries. All carriers shared a haplotype of 63–770 Kb, consistent with a single founder for this mutation. Using linkage dis- equilibrium analysis, the mutation was estimated to have originated between 650 and 900 years before ...