was predicted by the web based molecular modeling server, i-Tasser35 (http://zhanglab.ccmb.med.umich.edu/I-TASSER/). Model1 was the best predicted structural model with a confidence score (C-score) of 1.94; TM-score = 0.48 ± 0.15; RMSD 5.3 ± 3.4 Å by the...
Current regulatory requirements for supportive evidence include showing that delay in disease progression is accompanied by other indicators of clinical benefit7. To provide this evidence, large, long-term clinical trials are needed, the high cost of which inhibits the development of prediabetic medicina...