The LEGO® Learning- LEGO Education solutions are designed to develop STEAM learning in a way that’s both understandable and inspirational.
25] that likely stem from its health benefits and improvements to sleep duration, sleep efficiency, and reductions in sleep timing variability [25,26]. Participants report improved energy and restedness within a few weeks of beginning TRE that are sustained for at least six months post-interventio...
Most cases of acute myeloid leukemia (AML) involve the acquisition of recurrent mutations, and the subsequent clonal expansion of mutant hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). These are termed preleukemic mutations (pLM), and HSPCs that carry them are still ...
Abstract It has been suggested that new beta cells can arise from specific populations of adult pancreatic progenitors or facultative stem cells. However, their existence remains controversial, and the conditions under which they would contribute to new beta-cell formation are not clear. Here, we us...
Stem Cell Res Ther. 2019;10(1). Eslami N, Bahrehbar K, Esfandiari F, Shekari F, Hassani SN, Nazari A et al. Regenerative potential of different extracellular vesicle subpopulations derived from clonal mesenchymal stem cells in a mouse model of chemotherapy-induced premature ovarian failure. ...
ELISA kits were used to determine exosomal NOS3 (Jianglaibio, Shanghai, China, JL18188) and NO (Jianglaibio, JL15362) secretion according to manufacturer’s instructions. Immunofluorescence HUVECs seeded onto a cell climbing tablet in a 24-well plate were fixed, permeabilized, blocked, and ...
Biological responses of human mesenchymal stem cells to titanium wear debris particles. J Orthop Res. 2012;30(6):853-863. [30] Dalal A, Pawar V, Mcallister K, et al. Orthopedic implant cobalt- alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium...
ELISA kits were used to determine the levels of human RBP4 (KE00056, Proteintech, China), human LBP (KE00134, Proteintech, China), human TGF-β1 (BMS249-4, Thermo Fisher Scientific, USA) in serum samples or cell culture supernatants, following the manufacturer’s instruction. Signal detectio...
Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nat. Med. 18, 1095–1101 (2012). CAS PubMed PubMed Central Google Scholar Henriksen, K., Karsdal, M.A. & Martin, T.J. Osteoclast-derived coupling factors in bone remodeling. Calcif. Tissue Int. 94, ...
I. Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche. Int. J. Cancer 138, 417–427 (2016). Article CAS PubMed Google Scholar Murgai, M. et al. KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and...