A. et al. Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells. Sci. Adv. 6, eaax5692 (2020). Article CAS PubMed PubMed Central Google Sc
SUZ12 maintains self-renewal of alveolar macrophages, Langerhans cells, and HSC [9,26,69]. PRC2.1 and PRC2.2 both promote HSC maintenance [91., 92., 93.]. JARID2 also promotes myeloid differentiation and inflammation in macrophages [94]. Abbreviations: AEBP2, AE Binding Protein 2; EED,...
Privacy Protection in the Big Data Era: Judicial Renewal of the Right to be Forgotten Institution of PRCCong SunInternational Journal of Multiphysics
Our study reveals an epigenetic pathway that is essential for coordinating survival, self-renewal, and differentiation of stem cells in the developing brain. Results SNIP1 is required for the survival of NPCs in the murine embryonic brain We first examined the expression of Snip1 in the murine ...
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It has been proposed that the role of EZH2 in cancer is related to its activity in promoting self-renewal and maintaining the undifferentiated state of cells. The tar- get genes of EZH2 are generally oncosuppressor genes or those involved in cell differentiation; its deregulation promotes ...
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Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex Proc. Natl. Acad. Sci. USA, 107 (2010), pp. 15957-15962 CrossrefView in ScopusGoogle Scholar Petersen et al., 2017 M.A. Petersen, J.K. Ryu, K.J. Chang,...
It has been proposed that the role of EZH2 in cancer is related to its activity in promoting self-renewal and maintaining the undifferentiated state of cells. The tar- get genes of EZH2 are generally oncosuppressor genes or those involved in cell differentiation; its deregulation promotes ...
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