Pravastatin (Pravachol)- Uses, Side Effects, and More Medically Reviewed by Michelle Vermeulen, PharmD on Mar 24, 2024 | Written by WebMD Editorial Contributor Common Brand Name(s): Pravachol Common Generic Name(s): pravastatin, pravastatin Na, pravastatin sodium Pronunciation: PRAV-uh-stat-in...
Side effects Dosage information Patient tips During pregnancy Support group Drug class: statins Breastfeeding En español Patient resources Pravastatin drug information Professional resources Pravastatin Sodium monograph Other brands Pravachol Related treatment guides High Cholesterol High Cholesterol, Familial...
The incidence of side effects was low, the most common being gastrointestinal disturbances. There was no significant difference in the incidence or the distribution of adverse effects between the total intent-to-treat patient population and the previously untreated patients. Dosage administered also had...
as such, might theoretically blunt adrenal or gonadal steroid hormone production. Results of clinical trials with pravastatin in males and post-menopausal females were inconsistent with regard to possible effects of the drug on basal steroid hormone levels. In a study of 21 males, the meantestostero...
practical recommendations may although be established. There is no need to reduceatorvastatinandfluvastatindosage in patients with renal insufficiency whereaspravastatinandsimvastatindoses should be limited to their lowest level at initiation of therapy in theabsenceof sufficient data on their pharmacokinetics...
Monitor closely for adverse musculoskeletal effects, since history of renal impairment may be a risk factor for development of rhabdomyolysis. Dosage adjustments necessary in patients with severe renal impairment. Pharmacogenomic Considerations Genetic variation in the solute carrier organic anion transporter ...
The risk of skeletal muscle effects may be enhanced when pravastatin is used in combination withniacin; a reduction in PRAVACHOL dosage should be considered in this setting [seeWARNINGS AND PRECAUTIONS]. Warnings for Pravachol Included as part of the"PRECAUTIONS"Section ...
statistical power due to its premature stopping, the results of the GISSI-P suggest that a low-dose treatment with pravastatin (20 mg daily) is effective in reducing blood lipids, and underline the importance of long-term compliance with treatments in the search ...