Take pravastatin sodium tablets orally once daily as a single dose at any time of the day, with or without food. • For patients that require a high-intensity statin or are unable to achieve their LDL-C goal receiving pravastatin sodium tablets 80 mg daily, prescribe alternative LDL-C-lowe...
high-intensity statin therapy not possible (e.g., because of a contraindication or intolerable adverse effect), may consider moderate-intensity statin therapy (defined as reducing LDL-cholesterol concentrations by 30–49%).AHA/ACC considers pravastatin 40–80 mg daily to be a moderate-intensity ...
On the contrary, exposure to the higher dose of atorvastatin (100 ng/mL) significantly reduced the insulin release in response to either low (3.0 ± 0.3 µU/mL/islet; p < 0.05) and high glucose (7.3 ± 0.6 µU/mL/islet; p < 0.01), compared to the relative ...