We agree with these practice points about the use of diuretics and renin-angiotensin-aldosterone system (RAAS) inhibitors. We would like to particularly emphasize 2 points in this section. Practice Point 1.5.6. Counsel patients to hold ACEi or ARB and diuretics when at risk for volume depletion...
Dilation of the atria activates several molecular pathways, including the renin-angiotensin-aldosterone system (RAAS). Angiotensin II is upregulated in response to stretch (32), and atrial tissue from patients with persistent AF demonstrates increased expression of angiotensin-converting enzyme (ACE) (...
MATERIAL AND METHODS Data collection An online survey was designed to obtain preliminary infor- mation regarding the impact of advanced genetic testing on the time and workload of medical geneticists and genetic counselors around the world. The survey was sent to medical geneticists and genetic ...
Children resistant to CNIs may be treated with other steroid-sparing agents (see “Developing the PICO questions”; Fig.2and Supplementary TableS2). Patients with SRNS are defined as “multi-drug resistant” in the absence of complete remission after 12 months of treatment with 2 mechanistically ...
Potassium dysregulation can be life-threatening. Dietary potassium modification is a management strategy for hyperkalaemia. However, a 2017 review for clinical guidelines found no trials evaluating dietary restriction for managing hyperkalaemia in chronic kidney disease (CKD). Evidence regarding dietary hy...