第二节 DNA的结构Structure of DNA.ppt,戊糖 核糖 核酸的元素组成 1、 DNA双螺旋模型的提出 a.研究背景: 1950年,Chargaff从大量的不同来源的DNA样品的分析中发现了DNA组成的当量规律,即A=T,G=C,A+G=C+T。 不同生物种属的DNA碱基组成不同, 同一个体不同器官、不
ConstructionofDNAdoublehelixstructuremodel 沃森(J.D.Wstson)&克里克(F.Crick)卡文迪许实验室 生物学家 物理学家 经典遗传学发展之路 米歇尔:首先发现核酸 科塞尔:核酸含有嘌呤和嘧啶 科塞尔:1910年诺贝尔 生理学与医学奖 科塞尔 A·Kossel1853-1927 (1)1885至1901年间:(2)Kossel和他的学生经水解和化学...
The Information in DNA, continued Bases T and C have a single-ring structure and are classified as pyrimidines. A purine on one strand of a DNA molecule is always paired with a pyrimidine on the other strand. Specifically, adenine always pairs with thymine, and guanine always pairs with cyt...
Contents 2.1 Structure of DNA X~ray photograph of DNA with high quality:DNA specimens from different species have the same results(constant width; 3.4nm); Chargaff rules:the rule of the composition of DNA Physical chemistry studies and acid and alkali titrate studies on DNA base ; The bases ...
Discovering the structure of DNA Rosalind Franklin’s DNA image “Chargoff’s rule” A = T & C = G Cell division and DNA replication Cells divide Growth, Repair, Replacement Before cells divide they have to double cell structures, organelles and their genetic information ...
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dnapptnucleotidenucleotidesnucleicatpgujrat NucleotideandNucleicAcidNucleotideandNucleicAcid Dr.SajidMehmood AssistantProfessor HeadofDepartment DepartmentofBiochemistry NSMC,UniversityofGujrat Gujrat,Pakistan ChromatinStructureChromatinStructure NucleotidesNucleotides Nucleotidesareubiquitousmolecules withconsiderablestructuraldivers...
Effectsontranscription(geneexpression) Enhancesresponsiveness Mayalsoserveinpackaging NOTE:mostcellularDNAexistsasproteincontainingsupercoils DenaturationofDNA Denaturationbyheating. Howobserved? A260 FordsDNA, A260=1.0for50 0 君,已阅读到文档的结尾了呢~~ ...
the b and b pincers down tightly on the downstream DNA2. A major shift occurs in the N-terminal region of s (region 1.1) shifts. In the closed complex, s region 1.1 is in the active ce 26、nter; in the open complex, the region 1.1 shift to the outside of the center, allowing ...
1.Base(s)inDNAis(are)changedtoother(s),orabase(s)is(are)addedorremoved.2.Rearrangementsofthechromosomesoccurandarealsoconsidered.MedicalGenetics Mutationsareheritablechangesingeneticmaterial.MedicalGenetics 1.MutagensorMutagenicAgentsThesearesubstances,conditionsandformsthatsignificantlyincreasethefrequencyofmutations...