[11]Muriithi AK, Leung N, Valeri AM,et al. Biopsy-proven acute interstitial nephritis, 1993-2011: a case series. Am J Kidney Dis. 2014;64(4):558-66. [12]Lazarus B, Chen Y, Wilson FP, et al. Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease. JAMA Intern Med. 201...
参考文献: 1.Lazarus B, Chen Y, Wilson FP, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med. 2016;176:238-246. 2.http://www.medscape.com/viewarticle/858717 3.Moledina, Dennis G., and Mark A. Perazella. "PPIs and kidney disease: from AIN ...
根据PPIs的不良反应是否与其抑酸特性有关,可将其分为两类(图1): 与酸抑制无关的特异质反应包括过敏、急性间质性肾炎(acute interstitial nephritis,AIN)、慢性肾脏病(chronic kidney disease,CKD)、心血管疾病(cardiovascular disease,CVD)、痴呆和药物相互作用等 胃...
Proton Pump Inhibitors Augment the Risk of Major Adverse Cardiovascular Events and End-Stage Renal Disease in Patients With Acute Kidney Injury After Temporary Dialysis https://pubmed.ncbi.nlm./31901200/
[4]Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease.JAMA Intern Med 2016 Jan 11;238-246 [5]Association of Proton Pump Inhibitors With Risk of Dementia A Pharmacoepidemiological Claims Data Analysis JAMA Neurol.2016;73(4):410-416...
质⼦泵抑制剂（(proton pump inhibitor，PPI）为苯并咪唑类衍⽣物，能迅速穿过胃壁细胞膜，聚积在强酸性分泌⼩管中，转化为次磺酰胺类化合物，后者与H+K-—ATP酶a亚基中半胱氨酸残 基上的巯基作⽤，形成共价结合的⼆硫键，使H+K-—ATP酶失活，从⽽抑制其泌酸活性。PPI 是治疗酸相关疾病的⾸选...
Study findings presented at the American Society of Nephrology’s Kidney Week 2019 suggest a link between chronic use of proton pump inhibitors and progression of kidney function decline in chronic kidney disease.
[4]Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease.JAMA Intern Med 2016 Jan 11;238-246 [5]Association of Proton Pump Inhibitors With Risk of Dementia A Pharmacoepidemiological Claims Data Analysis JAMA Neurol.2016;73(4):410-416...
Background: Reports of adverse outcomes with use of Proton Pump Inhibitors (PPIs) and recent associations between PPI use and Chronic Kidney Disease (CKD) suggest the need to examine PPI use in the general popu-lation.Devraj, RadhikaDeshpande, Maithili...
Previous studies have suggested that many people who use proton pump inhibitors (PPIs) might not have a clinical indication for doing so, which is concerning because PPIs have been associated with chronic kidney disease and infection in some observatio...