The peroxisome proliferator-activated receptor (PPAR) signaling pathway plays a crucial role in systemic cell metabolism, energy homeostasis and immune response inhibition. However, its significance in hepatocellular carcinoma (HCC) has not been well documented. In our study, based on the RNA ...
KEGG pathway analysis indicated that IVF-ET manipulation extensively over-activated PPAR signaling pathway. Immune tolerance, trophoblast invasion, syncytia formation, lipid and glucose metabolism, inflammatory response and other complex biological functions were disturbed. RT-qPCR results and proteins staining...
PPAR Signaling Partnership In between Psychiatric Inpatient Bedrooms as well as Posted onJanuary 4, 2025 Reply Finally, SlBBX20 promotes the accumulation of steroidal glycoalkaloids and attenuates Botrytis cinerea disease. This work clearly demonstrates that BBX proteins are multilayer regulators of plant ...
摘要: Purpose Neoadjuvant chemotherapy for advanced breast cancer may improve the radicality for a subset of patients, but others may suffer from severe adverse drug reactions without any benefit. To...关键词: Neoadjuvant Gene expression Chemotherapy response PPAR pathway DNA repair ...
1990年,有研究发现这些化合物的共同受体便是从小鼠肝脏中提取出来的蛋白物质,该蛋白被广泛称为过氧化物酶体增殖物激活受体(PPAR)[2]。过氧化物酶体增殖物激活受体(PPAR)已确定包括三种亚型,分别为PPARα(NR1C1)、 PPARδ/β(NR1C2)、 PPARγ(NR1C3)[3],该受体属于核受体(NR)超家族,是配体激活后调节...
(Peroxisome Proliferator Activated Receptor),DNA repair and ER signal pathways and in the immune-related gene cluster.The qRT-PCR analysis results for the genes in the PPAR pathway(LPL,SORBSl,PLTP,SCD5,MMPl and CSTA) in independent validation set were consistent with the results from the ...
ulcerative colitis and rheumatoid arthritis.This review mainly focuses on the interaction between PPARs and TLR-NF-κB signaling pathway either in para-inflammatory status or pathological state,which highlights the importance of PPARs in the process of inflammation and immune responses and provides new...
much better mimic in vivo circumstances in comparison to conventional monolayer fixed culture.Immune cells play an important part when you look at the improvement disease, from being able to inhibit it by secreting pro-inflammatory mediators, to assist in its development by secreting growth factors,...
(Leishmania) chagasi indicate differences in the regulation of genes involved in signaling, motility and the immune response.Results show that the early (... Carolina,Ramírez,Yira,... - 《Plos Neglected Tropical Diseases》 被引量: 29发表: 2012年 Transforming Growth Factor-β (TGF-β) Activate...
PPAR-γ coupled signaling pathways involved in rat liver regeneration; PPAR-γ偶联的信号通路可能参与大鼠肝再生 2) Signal pathway 信号通路 1. Wnt signal pathway and tooth development; Wnt信号通路与牙胚发育 2. Transforming growth factor-beta-Smad signal pathway in the development of palate; ...