主题词： PPAR-γ;AP-1;信号通路;疾病 摘要：PPAR-γ/AP-1信号通路是调控细胞增殖、分化和转移,参与炎症反应的重要信号转导途径.近年来,PPAR-γ通过直接抑制转录因子AP-1的激活或间接拮抗辅助调节因子在相关疾病中被广泛关注,本研究综述该信号通路在心血管系统、肾脏系统、免疫系统及其他系统关系的研究进展,旨在为...
16643-1-AP targets PPAR Gamma in WB, IHC, IF-P, FC (Intra), IP, CoIP, CHIP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications WB, IHC, IF-P, FC (Intra), IP, ELISA Application Description Cited Applications WB, IHC, IF, IP, CoIP, CHIP ...
22061-1-AP targets PPAR Gamma in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications WB, IHC, ELISA Application Description Cited Applications WB, IHC Tested Reactivity human, mouse, rat Cited Reactivity human, mouse, rat Immunogen PPAR Gamma fus...
激活蛋白1炎症反应目的:本研究主要观察激活过氧化物酶体增殖物激活受体γ(Peroxisome proliferatoractivated receptorγ,PPARγ)对结核分枝杆菌(mycobacterium tuberculosis,MTB)感染小鼠肺组织激活蛋白-1(Activator protein-1,AP-1)表达及炎症反应的影响,旨在进一步了解结核病的致病机制,为结核病的防治提供理论依据,为抗结核...
CIMT1, NR1C3, PPAR gamma, PPARG, PPARG2, PPARγ Print datasheet MSDS Validation Data Gallery Filter: AllWBIHC WB analysis using 22061-1-AP Various lysates were subjected to SDS PAGE followed by western blot with 22061-1-AP (PPAR Gamma antibody) at dilution of 1:3000 incubated at room ...
PPARγ同样也与炎症有关。人们设想在单核细胞和巨噬细胞中,PPARγ通过抑制炎症转录因子前体如AP-1、STAT和NK-K的活性来降低细胞因子(TNFα、白细胞介素-1β和白细胞介素-6)的生成。PPARγ的抗炎症作用在动脉粥样硬化治疗中十分有用。此外,PPARγ还降低了与斑块去稳定化有关的金属蛋白酶如MMP-9的表达量。
16643-1-AP targets PPAR Gamma in WB, IHC, IF-P, FC (Intra), IP, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Reactivity human, mouse, rat Cited Reactivity human, mouse, rat, pig, rabbit, chicken, zebrafish, hamster, sheep, goat Host /...
内容提示: PPAR -γ/AP -1 信号通路在相关疾病中作用的研究进展刘冬梅 1 ,肖美先 2 ,王海利 1 ,赵晓杰 1 ,韩晓群 3*(1. 宜春学院 化学与生物工程学院;2. 宜春市袁州区疾病预防控制中心;3. 宜春学院 医学院,江西 宜春336000)收稿日期:2020 -08 -04基金项目:国家自然科学基金 (项目编号:81760356)。
摘要: PPAR-γ/AP-1信号通路是调控细胞增殖,分化和转移,参与炎症反应的重要信号转导途径.近年来,PPAR-γ通过直接抑制转录因子AP-1的激活或间接拮抗辅助调节因子在相关疾病中被广泛关注,本研究综述该信号通路在心血管系统,肾脏系统,免疫系统及其他系统关系的研究进展,旨在为其治疗提供新的靶点和策略.关键词:...
Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia. Cell Death Differ.21:655-64. 20... G,Schett,EF,... - 《Cell Death & Differentiation》 被引量: 17发表: 2014年 and hypoxia Fra-2|[sol]|AP-1 controls adipocyte differentiation and survival by reg...