In this paper, we consider sparse signal identification in genome-wide association studies and present two analytical frameworks for detailed analysis of the statistical power for detecting and identifying the disease-associated variants. We present an explicit sample size formula for achieving a given ...
In our study, the sample size for the SFb rate experiment was chosen based on common practice in monkey laser-induced CNV experiments (Festing, 2018; Ryan, 1979, 1982). The sample sizes (n) for the anti-VEGF experiment were estimated by the formula n = [2(Zα+Z1–β)2 ]/SES2 (...
psychometrika https://doi.org/10.1007/s11336-019-09692-3 POWER ANALYSIS AND SAMPLE SIZE PLANNING IN ANCOVA DESIGNS Gwowen Shieh NATIONAL CHIAO TUNG UNIVERSITY The analysis of covariance (ANCOVA) has notably proven to be an effective tool in a broad range of scientific applications. Despite the ...
In particular, no sample size formula for cost-effectiveness analysis is available for analysts hoping either to calculate the required sample size at the design stage of a study or to calculate the power a given size of clinical trial will generate for cost-effectiveness analysis. Building on ...
sampleSizeZtest = function(alpha = 0.05, sigma, power, delta){ zcra=qnorm(p = 1-alpha, mean = 0, sd=1) zcrb=qnorm(p = power, mean = 0, sd = 1) n = round(((zcra+zcrb)*sigma)/delta)^2) return(n) } ### Load pwr package to perform power and sample size analysis li...
We derive an explicit form for power/sample size calculation based on these two tests. A number of simulation studies have been used to illustrate the efficiency of the tests for the case-cohort design. An example is provided on how to use the formula. 展开 关键词:...
The hidden factor: accounting for covariate effects in power and sample size computation for a binary trait Accurate power and sample size estimation are crucial to the design and analysis of genetic association studies. When analyzing a binary trait via logistic... Z Zhang,L Sun 被引量: 0发表...
Case-Control Studies: Design, Conduct, Analysis (1982) RGD Steel et al. Principles and Procedures of Statistics: A Biometrical Approach (1980) JL Fleiss Statistical Methods for Rates and Proportions (1981) JT Casagrande et al. An improved approximate formula for calculating sample sizes for compari...
Power and Sample Size for MANOVA and Repeated Measures with the GLMPOWER Procedure Power analysis helps you plan a study that has a controlled probability of detecting a meaningful effect, giving you conclusive results with maximum efficiency. SAS/STAT provides two procedures for performing sample si...
"Exact and approximate power and sample size calculations for analysis of covariance in randomized clinical trials with or without stratification" by Yongq... Tang (2018b,a) derived the exact power formulae for t tests and analysis of covariance (ANCOVA) in superiority, noninferiority and equival...