PASS（Power Analysis and Sample Size）是用于效能分析和样本量估计的统计软件包，是市场研究中最好的...
Power Analysis and Sample Size Determination for Crossover Trials with Application to Bioequivalence Assessment of Topical Ophthalmic Drugs Using Serial Sa... Objective To develop methods for determining a suitable sample size for bioequivalence assessment of generic topical ophthalmic drugs using crossover...
In metabolic phenotyping studies, sample size determination remains a complex step. This is due particularly to the multiple hypothesis-testing framework and ... B Elise,N Vincent,BJ Blaise - 《Briefings in Bioinformatics》 被引量: 4发表: 2015年 Statistical analysis in metabolic phenotyping Metabolic...
Generally, bioequivalence is assessed by comparing the area under the concentration-time curve (AUC) and the maximal concentration (Cmax)[2]. According to regulatory guidelines, noncompartmental analysis (NCA) is recommended to estimate AUC and Cmax. In a common NCA analysis, all of the subjects...
Power analysis and sample size estimation for sequence-based RV association studies are challenging because of the necessity to realistically model the underlying allelic architecture of complex diseases within a suitable analytical framework to assess the performance of a variety of RV association methods...
Finally, a local optimal power is achievable for a given budget constraint, and the dominant contributing factor is sample size rather than the sequencing depth. In conclusion, we provide a power analysis tool (http://www2.hawaii.edu/~lgarmire/RNASeqPowerCalculator.htm) that captures the ...
Software Reviews : NCSS: Power Analysis and Sample Size (PASS)Publisher: Jerry L. Hintze, 329 N. 1000 East, Kaysville, UT 84037; 8oi- 546-0445; FAX 801-546-3907 Year of Publication: 1991 Version Reviewed: i.o Materials: 248-page manual, 4 5.25\" disks Price: $149 Machine ...
Statistical power analysis characterizes the ability of a study to detect a meaningful effect size—for exam-ple, the difference between two population means. It also determines the sample size required to pro-vide a desired power for an effect of scientific interest. Proper planning reduces the ...
The sample size calculations are then recalculated using a non-inferiority margin, to ensure that the NMB sample size for the trial was also sufficient to demonstrate non-inferiority for the effectiveness endpoint. Finally, a probabilistic analysis explored uncertainty in the model parameters and the...
PASS is an extremely user-friendly software tool for power analysis and sample size estimation for testing statistical hypotheses of varying nature in clinical, pharmaceutical and medical research settings. The present write up makes an attempt to evaluate its powerful modules namely – 'group sequentia...