Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis. Dis Colon Rectum Jun 2003;46(6):748-53.Shen B, Achkar JP, Connor JT, et al. Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis. Dis Colon Rectum. 2003;...
OBJECTIVE: To develop a "Pouchitis Disease Activity Index" (PDAI) and to compare it with other diagnostic scoring systems for pouchitis. DESIGN: We compared patients who had an optimal outcome with those who had a poor result attributable to recurrent pouchitis after ileal pouch-anal anastomosis ...
A clinical diagnosis should be always confirmed by endoscopy and histology, and Pouchitis Disease Activity Index (PDAI), based on clinical symptoms, endoscopic appearance and histologic findings, represents an objective and reproducible scoring system for pouchitis. The treatment of pouchitis is largely ...
Sandborn et al., "Pouchitis After Ileal Pouch-Anal Anastomosis: A Pouchitis Disease Activity Index," Mayo Clin. Proc. 69:409-415 (1994). Sandborn, "Pouchitis Following Ileal Pouch-Anal Anastomosis: Definition, Pathogenesis, and Treatment," Gastroenterol. 107:1856-1860 (1994). Sandborn et...
Clinical assessment, endoscopic and histological evaluations were performed before and after therapy using the Pouchitis Disease Activity Index (PDAI) score. Improvement was defined as a decrease of at least three points in the PDAI score and remission as a PDAI score of 0. The Wilcoxon signed ...
The efficacy of the treatment was assessed by comparing Pouchitis Disease Activity Index (PDAI) scores. A PDAI score > 7 suggests a diagnosis of pouchitis. Complete remission and clinical response were defined a clinical subscore of 0 points and a clinical subscore decrease of more than 3 ...
Asymptomatic patients with a Pouchitis Disease Activity Index (PDAI) symptom sub-score of zero who underwent an index surveillance pouchoscopy were included. Endoscopic pouch body activity was graded as 0: normal, 1: mucosal inflammation, or 2: mucosal breaks (ulcers and/or erosions). The ...
Patients were randomized to Adalimumab or placebo for 12 weeks. Primary outcome was reduction in clinical pouchitis disease activity index (PDAI) of ≥2 at any time. Secondary endpoints were remission of pouchitis, endoscopic and histologic effect and quality of life. Results: Thirteen patients were...
A modified pouchitis disease activity index of 鈮 5 was defined as pouchitis. Potential preoperative, intraoperative, and postoperative predictors for pouchitis including various demographic and clinical variables were analyzed using Cox regression analysis, Students' t-tests, Mann-Whitney U tests, and ...
A clinical diagnosis should be always confirmed by endoscopy and histology, and Pouchitis Disease Activity Index (PDAI), based on clinical symptoms, endoscopic appearance and histologic findings, represents an objective and reproducible scoring system for pouchitis. The treatment of pouchitis is largely ...