The close relationship between diclofenac and pantoprazole, and the cytochrome P450 and P-glycoprotein systems offers a strong indication that a drug interaction may be occurring. While evaluating the side effects of drugs in patients undergoing monotherapy, clinicians should also consider the mechanisms ...
The surge in bacterial growth and the escalating resistance against a multitude of antibiotic drugs have burgeoned into an alarming global threat, necessitating urgent and innovative interventions. In response to this peril, scientists have embarked on the development of advanced biocompatible antibacterial...
developed a sustained release formulation of rifampicin in which rifampicin was incorporated in a nanostructured ion-pair complex of low-molecular weight chitosan and soy-lecithin which improved the permeability [188,189]. Srinivas et al. developed a sustained release formulation of diclofenac sodium by...
Individuals diagnosed with acute arthritis were given an oral infusion of Urtica dioica (50 mg) and 50 mg of diclofenac daily. These findings indicate that U. dioica has a remarkable synergistic impact when taken with NSAIDs. It has been demonstrated that in chondrocytes, along with nettle ...
curve of H-G60 at − 20 °C.jThe hydrogel is connected to the circuit at − 20 °C for 2 h and the light emitting diode (LED) bulb is very bright. Reproduced with permission [84]. Copyright 2022, American Chemical Society. 3D three dimensions, DS diclofenac sodium, MF ...
CEO also exhibited significant in-vitro anti-inflammatory activity with IC 50 -29.71 ± 1.95 g/ml as compared to that of Diclofenac sodium (IC 50 -36.52 ± 1.95 g/ml). Molecular docking revealed that β-caryophyllene showed considerable binding potential with human peroxiredoxin 5 receptor (-...
A polysaccharide hydrogel was isolated from the seeds of Tamarindus indica (tamarind) and was used as release modifier for the preparation of diclofenac so... Giriraj,T.,Kulkarni,... - 《Drug Delivery》 被引量: 86发表: 2008年 Dried Whole Plant Artemisia annua as an Antimalarial Therapy Drugs...
However, the standard compound, diclofenac exhibited more dominant effect with 55.56% and 78.45% at 5 and 10 mg/kg i.p., respectively (Figure 5). Figure 4 The effect (%) of crude extract/fractions in acetic acid induced writhing test ( n = 6). The data were analyzed by analysis of ...
Piperine is a type of amide alkaloid that exhibits pleiotropic properties like antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective, neuroprotective and enhancing bioavailability and fertility-related activities. Piperine has th
these diseases; however, most of them remain incurable because of drug resistance. In addition, some natural products are not free from side effects. Therefore, the search and discovery of novel plant-derived products are essential to improve the impact and outcome of plant-based therapeutic ...