2009). Potassium channels are present in the plasma membrane and intracellular organelles of all cells. They play a critical role in regulation of neuronal excitability, duration of action potential, secretion of hormones, smooth muscle relaxation, and repolarization of cardiac muscles (Sandhiya and ...
Therefore, it is pivotal in E–C coupling and the duration of action potential. The CaVα1 subunit is regulated by different accessory subunits through interacting with them (Fig. 1). It is prevailingly associated with 4 distinct β-isoforms (CaVβ1 to CaVβ4) and 4 distinct α2-δ-...
Increase in [Na + ] i (Na-methane sulfonate) also caused its decrease, although this effect was weaker than that of K + . The action of these monovalent cations on the duration of the action potential is the opposite of their action on the membrane from the outside ( cf . Shimmen, ...
Buffered Pfizerpen (penicillin G potassium) for Injection is highly water soluble. It may be dissolved in small amounts of Water for Injection, or SterileIsotonic Sodium Chloride Solution for Parenteral Use. All solutions should be stored in a refrigerator. When refrigerated, penicillin solutions may...
The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may ...
The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may ...
Solid lines through the 0.0 0.0 0.2 0.4 0.6 0.8 1.0 Step duration (ms) Figure 3 | Fast and slow components of K þ charge movement are kinetically independent. (a) Experimental protocol. Superimposed H2DTG- sensitive currents in response to a voltage jump to À 160 mV with step ...
Sympathetic nervous system (SNS) regulation of cardiac action potential duration (APD) is mediated by beta adrenergic receptor (betaAR) activation, which i... Marx,O S. - 《Science》 被引量: 1185发表: 2002年 Chloride and potassium channels in cystic fibrosis airway epithelia Cystic fibrosis, ...
Bassingthwaite, J. B., Fry, C. H., and McGuigan, J. A. S., 1976, Relationship between intracellular calcium and outward current in mammalian ventricular muscle; a mechanism for the control of action potential duration?J. Physiol. (London)262:15–37. ...
Ethacrynic acid is well absorbed from the gastrointestinal tract following oral administration and displays a rapid onset and brief duration of action. It can also be administered parenterally to treat medical emergencies, such as acute pulmonary edema. The diuresis observed following ethacrynic acid...