gastroesophageal reflux diseasehelicobacter pylorinonerosive esophagitispeptic ulcerpotassium-competitive acid blockersproton pump inhibitorPotassium-competitive acid blockers (PCABs) represent a new class of compounds for the treatment of acid-related disorders. Recent FDA approval of the PCAB vonoprazan for...
The past century has been dominated by the Schwartz’ dictum “No acid, no ulcer” [1]. Indeed, the role of acid in the pathophysiology of gastric mucosal lesions represented the impetus guiding research into the treatment of acid-related diseases. Although antacids and anticholinergics were, u...
potassium- a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite ...
Acetates=(1) Metallic salts derived from acetic acid by interaction of the metallic oxide, hydroxide, or carbonate with the acid; or the esters derived by interaction of alcohols with acetic acid, which include the common esters of ethyl, propyl, isopropyl, butyl, and amyl acetates. (2) A...
The First-in-class potassium-competitive acid blocker, vonoprazan fumarate: pharmacokinetic anddoi:10.1111/apt.13487Sachs, G.Scott, D. R.John Wiley & Sons, Ltd.Alimentary Pharmacology & Therapeutics... G Sachs,DR Scott - 《Alimentary Pharmacology & Therapeutics》 被引量: 2发表: 2016年 ...
, K+ ions are pumped through the blood to all vital organs. Potassium's importance to the physiological system cannot be overstated: It plays a crucial role in electrical pulse transmission along nerve fibers; protein synthesis; acid-base balance; and formation of collagen, elastin, and muscle....
The tubes are then placed in a sand bath on a hot plate so that the acid refluxes. When the tubes have been heated for five minutes, each is removed from the sand bath and agitated so that the fibrin comes in contact with the acid. The tubes are returned to the sand bath and a ...
Current treatments for gastroesophageal reflux disease (GERD) and other acid-related disorders either block stimulation of the parietal cell (H2-receptor a... JP Kothadia,CW Howden - 《Foregut》 被引量: 0发表: 2024年 Atrophic gastritis with Helicobacter pylori infection is promoted by anti-parieta...
Polyacrylic acid (PAA) has high water absorbency but poor salt resistance. Humic acid (HA) extracted from lignite was introduced into the cross-linked copolymer systems of AA to improve the water absorbency and salt-tolerance. A polyacrylic acid-potassium humate (PAA-KHA) coated ammonium dihydrogen...
Potassiumis one of the electrolytes that with sodium is involved in the maintenance of normal water balance, osmotic equilibrium, acid-base balance, and it is crucial to cardiovascular and nerve functions. It is also the primary positive cation found within the cells, and along with calcium serve...