This article presents a study which examined the treatments for postherpetic neuralgia. The tricyclic antidepressants amitriptyline and desipramine are considered effective in relieving pain from established postherpetic neuralgia. Topical capsaicin has promise, but cannot be recommended strongly based on the...
Postherpetic neuralgia: a workable treatment plan. 来自 NCBI 喜欢 0 阅读量: 49 作者: RK Portenoy 摘要: Management of established should proceed on several fronts simultaneously and may include pain-oriented treatments that are pharmacologic, neuroaugmentative, anesthetic, physiatric, psychological, ...
The FDA has approved a topical 8% patch formulation of capsaicin (Qutenza-NeurogesX), available only by prescription, for local treatment of postherpetic neuralgia. Postherpetic neuralgia occurs after herpes zoster in about one third of patients ≥60 years old and can persist for months or even ...
The effectiveness of topical applications of capsaicin (truns-8-methyl-N-vanillyl-6-nonamide) in relieving pain was studied in 50 patients with a 2-month to 19-year history of postherpetic neuralgia unresponsive, or poorly responsive, to oral analgesics, antidepressants and neuroleptic agents. Of...
Postherpetic neuralgia (PHN) is a chronic pain disorder that results from reactivation of varicella zoster.1, 2, 3, 4, 5 Treatments for PHN are often restricted owing to adverse effects and poor tolerability (tricyclic antidepressants, opioids, and anticonvulsants), their slow onset of action (...
February 7, 2011 (New Orleans, Louisiana) — Acute administration of gabapentin reduces the incidence of postherpetic neuralgia (PHN), and might even prevent it from developing if administered when the first herpes zoster vesicle appears, according to research presented during a late-breaking abstract...
No new safety concerns emerged. Conclusions and Relevance Crisugabalin, 40 mg/d, or crisugabalin, 80 mg/d, was well tolerated and demonstrated a statistically significant improvement in ADPS over placebo. Trial Registration ClinicalTrials.gov Identifier: NCT05140863 Introduction Postherpetic neuralgia ...
(HZ), we conducted a prospective, observational study to evaluate (1) the Zoster Brief Pain Inventory (ZBPI), an HZ-specific questionnaire to quantify HZ pain and discomfort, (2) an operational definition of postherpetic neuralgia (PHN), and (3) a severity-duration measure of the burden of...
Postherpetic neuralgia (PHN) is a chronic pain syndrome that is often refractory to treatment and can last for years, causing physical and social disability, psychological distress, and increased use of the healthcare system. In this paper we provide an update on recent developments in the ...
Postherpetic neuralgia (PHN) is a separate disease entity that represents a complication of acute herpes zoster. PHN, involving aberrant somatosen‐sory processing in the peripheral and/or central nervous system, is considered to be a chronic neuropathic pain, frequently unresponsive to all treatment ...