Genetic regulationMicroRNA - mRNA Regulation Networks Post-transcriptional RegulationWerner DubitzkyOlaf WolkenhauerKwangHyun ChoHiroki YokotaSpringer New YorkYoon J-H, Abdelmohsen K, Gorospe M (2013) Posttranscriptional gene regulation by long
Post-Transcriptional Gene Regulation (PTGR) MicroRNA - mRNA Regulation Networks Post-transcriptional Regulation W Dubitzky,O Wolkenhauer,KH Cho,... - Springer New York 被引量: 2发表: 2013年 Post-transcriptional gene regulation during seed germination and stand establishment Seed germination and stan...
We then discuss some prospects of post-transcriptional modification in the therapy of infectious or other immune related diseases and the development of mRNA vaccines.中心法则(central dogma)揭示了遗传信息从基因组DNA通过转录传递给信使RNA(messenger RNA, mRNA), 再以mRNA为模板通过翻译传递给蛋白质的过程....
In theory, the depletion and enrichment of miRNAs during a stage transition should attenuate and enhance, respectively, post-transcriptional suppression of target genes. Therefore, we sought to identify genes that are subject to significant post-transcriptional (PT) regulation during each stage transition...
Cancer Gene Therapy volume 30, pages 529–547 (2023)Cite this article 3831 Accesses 57 Citations Metrics details Abstract Posttranslational modifications (PTMs) of proteins, the major mechanism of protein function regulation, play important roles in regulating a variety of cellular physiological and...
Post-translational modifications (PTMs) can occur on specific amino acids localized within regulatory domains of target proteins, which control a protein’s stability. These regions, called degrons, are often controlled by PTMs, which act as signals to e
In addition to transcriptional regulation, gene expression in fruit ripening can also be modulated by epigenetic or translational control [20–22]. However, unlike the relatively well studied and defined changes in the fruit transcriptome during ripening, little is known about its post-transcriptional ...
“turntable model” here. Crosstalk between PTMs and LLPS has been implicated in numerous areas of illness and biological function, i.e., neurodegenerative diseases, tumors, viral infections, environmental stress, DNA damage repair, transcriptional regulation, signal transduction, and cell homeostasis ...
ADP-ribosylation, which refers to the enzymatic transfer of one or more ADP-ribose from NAD + to the acceptor proteins [226], has been recognized as an important regulator in a wide range of biological processes, including DNA damage responses, transcriptional regulation, cell death as well...
PTMs and atherosclerosis Atherosclerosis is a chronic inflammatory cardiovascular disease that poses a significant threat to human health. In atherosclerotic lesions, modification by SUMO is involved in the regulation and localization of the transcriptional activity and stability of target proteins. Liver X...