Post-stroke cognitive impairment (PSCI) is a major stroke consequence that has a severe impact on patients' quality of life and survival rate. For this reason, it is especially crucial to identify and intervene early in high-risk groups during the acute phase of stroke. Current...
G-CSF treatment after stroke exerted a robust and sustained beneficial effect on survival rate and running function. Transient improvement after G-CSF treatment could be observed for coordinative motor function on the inclined plane test and for working memory in the radial maze test. At cellular ...
The researchers have discovered that patients with ischemic stroke attributable to SVD have poorer long-term survival compared to stroke patients without SVD. Findings indicate an association between poor survival in patients with SVD and increased risk of cardiac death.Jones...
Many studies suggest that post-stroke vulnerability of the brain can induce PSD and PSD is associated with reduced recovery after stroke in stroke survival patients. However, until now there is no clear evidence to support the etiological mechanisms of PSD, which seems to be a multifactorial disea...
Survival was followed up to 5 years after stroke (median 1.5 years). Independent predictors of death were identified by means of a survival model based on 13,242 individuals with a complete data set. Results: Compared to normal-weight patients, mortality was lower in overweight [hazard rate (...
Early antidepressant treatment of PSD appears to enhance both physical and cognitive recovery from stroke and might increase survival up to 10 years following stroke. There has also been progress in understanding the pathophysiology of PSD. Inflammatory processes might be associated with the onset of ...
Rehabilitation treatments and services are essential for the recovery of post-stroke patients’ functions; however, the increasing number of available therapies and the lack of consensus among outcome measures compromises the possibility to determine an appropriate level of evidence. Machine learning techniq...
Post-stroke depression (PSD) affects millions of patients who suffer cerebral stroke. However, the molecular mechanisms and pathophysiology are poorly understood. Previous studies have shown that exosomes have been proven to be involved in neuropsychiatr
Although depression may affect patients' recovery and even their survival rate after stroke, it is often overlooked or inadequately managed. And data regarding the treatment efficacy and safety of fluoxetine in this setting are inconsistent. We aimed to systematically assess those two indices in patien...
Stroke (infarction or haemorrhage) is an important cause of epilepsy in adulthood, especially in the elderly. Because of a high incidence and improved survival, post-stroke epilepsy (PSE) is a great contemporary challenge for physicians. In our studies we have defined PSE as two or more seizure...