Post-mortem genetic analysis of sudden unexplained death in a young cohort: a whole-exome sequencing studyCHINASUDDEN deathGENETIC testingGENETIC variationNEMALINE myopathyCOMPUTER-assisted drug designSudden unexplained death (SUD) constitutes a considerable portion of unexpected ...
Call For Post-Mortem Genetic Testing To Become Routine In Cases Of Sudden Death
Post-mortem genetic testing by using massive parallel sequencing (MPS) approaches represents an efficient and rapid tool to further investigate unexplained death cases and might help to elucidate pathogenic genetic variants and mechanisms in cases without a conclusive cause of death. In this study, we...
European Journal of Human Genetics (2016) 24, 1104–1111 & 2016 Macmillan Publishers Limited All rights reserved 1018-4813/16 www.nature.com/ejhg ARTICLE Post-mortem testing; germline BRCA1/2 variant detection using archival FFPE non-tumor tissue. A new paradigm in genetic counseling Annabeth ...
Sudden death: ethical and legal problems of post-mortem forensic genetic testing for hereditary cardiac diseases Clin Genet, 77 (2010), pp. 287-292 CrossrefView in ScopusGoogle Scholar [3] F. Fellmann, K. Michaud Mort subite cardiaque dans la famille : quel bilan chez les proches ? Real...
However, forensic mortuaries do not retain DNA samples in all cases, which hinders subsequent genetic testing if it is later deemed necessary. This study aimed to evaluate whether post-mortem whole blood samples collected for toxicological analysis, could provide viable DNA for genetic testing after ...
When human genetic data are collected for the purposes of forensic medicine or in civil, criminal and other legal proceedings, including parentage testing, requests for the collectionofbiological samples, in vivoorpost-mortem,should be made only in accordance with national legislation or regulation, ...
Genetic rescue of an endangered mammal by cross-species nuclear transfer using post-mortem somatic cells. Since the advent of procedures for cloning animals, conservation biologists have proposed using this technology to preserve endangered mammals. Here we rep... P Loi,G Ptak,B Barboni,... - ...
Both epidemiological and genetic studies support a role of neuroinflammation in the pathophysiology of Parkinson's disease (PD). Furthermore, post mortem s... EC Hirsch,S Vyas,S Hunot - 《Parkinsonism & Related Disorders》 被引量: 1184发表: 2012年 ...
As linear discriminant analysis is constrained to assign every sample to one class, we performed additional analyses to confirm that controls and post-mortem expression data from different brain regions assigned to each molecular phenotype can be distinguished from motor-cortex case samples. To determine...