▸ Is there any pattern to the circumstances under which they occur—for example, time of day (morning myoclonus), relation to particular activities (syncope) or acute emotional distress (psychogenic non-epileptic seizures)? Sleep deprivation, fever, and alcohol are common triggers of epileptic ...
Your risk of ablood clotis very small. Only one out of every 1,000 women who takebirth control pillseach year will get a blood clot. The patch and ring also slightly increase your risk. You're more likely to get a blood clot if you: ...
Migraineurs with frequent aura (≥1 per month) are at a 12-fold increased risk of posterior circulation infarctions. Although the mechanism is unclear, these lesions are located in the arterial borderzone of the cerebellum. This case illustrates, for the first time, crossed cerebellar diaschisis...
Membrane poration by dynorphins may represent a mechanism of pathological signal transduction. Persistent neuronal excitation by this mechanism may lead to profound neuropathological alterations, including neurodegeneration and cell death. Cell Death and Disease (2015) 6, e1683; doi:10.1038/cddis....
Among many inflammatory triggers and mediators, both experimental and clinical data have suggested IL-1β as the most potent pro-inflammatory cytokine in neurodegeneration. First, a genetic study has shown that the inheritance of a specific IL-1 gene polymorphism is associated with an earlier age ...
The primary objective of mobile phone technology is to achieve communication with any person at any place and time. In the modern era, it is impossible to
(ID), the aims of this work were to (1) identify a set of methods for assessing the validity of reported seizure triggers in individual patients; and (2) undertake an initial assessment of the ease of implementation and acceptability of the method by applying it to a series of cases.Illi...
Reflex seizures are typically associated with extrinsic sensory triggers; however, intrinsic cognitive or proprioceptive triggers have also been assessed. The identification of a trigger underlying a seizure may be more difficult if it is intrinsic and complex, and if triggering mechanisms are ...
BACKGROUND: High extracellular glutamate concentrations have been identified as a likely trigger of epileptic seizures in mesial temporal lobe epilepsy (MTLE), but the underlying mechanism remains unclear. We investigated whether a deficiency in glutamine synthetase, a key enzyme in catabolism of ...
The induction of a cytokine storm in systemic circulation can trigger a neuroinflammatory cascade, which can subsequently compromise the blood-brain barrier and activate microglia- and astrocyte-borne Toll-like receptors, thereby leading to neuronal tissue damage. Hence, a holistic approach should be ...