Triple-negativebreast cancer, or TNBC, affects 10–15% of patients with breast cancer in the US. TNBC is called "triple-negative" because the cancer lacks anestrogen receptor, aprogesterone receptor, and a HER2 (human epidermal growth factor) receptor. The absence of any of these receptors—r...
1099 Background: Metastatic breast cancer (MBC) is a lethal disease and is generally only amenable to systemic treatment. Although increasingly recommended on selected patients, local treatments, and particularly surgery, are seldom used in the therapeutic armamentarium for MBC and their long-term ...
This marker makes drug production possible for metastatic BLBC in the near future, the study noted. BLBC, referred to as triple-negative breast cancer, is unresponsive to many traditional treatments, is much more likely to metastasize, and has a poor prognosis once diagnosed. In addition to crea...
The findings of this study align with previous literature, which also show the benefits ofbariatric surgerysuch as weight loss and improved lung function. For this study, researchers were focused on understanding the mechanisms behind these improvements in hopes of developing new treatments for obese ...
Some breast cancer treatments can make you infertile for a while. In some cases, treatments could make you infertile forever. The effect depends in part on how long you’re on treatment, the dosage, your age, and other things. Here are some ways that cancer therapies can affect your fertil...
you experience. Topical estrogen creams applied to the vaginal area also can be used. However, women with hormone-sensitive breast or ovarian cancer should carefully discuss any type of hormone therapy with their doctors. Many of these conditions may respond to treatments that do not use hormones...
In terms of treatment de-escalation, I discussed the importance of appropriately selecting patients for less toxic treatments, because a lot of those patients will do just as well without polychemotherapy and additional HER2-directed regimens.HER2-positive breast cancer is heterogeneous, and different ...
Reproducibility of measurements of oestrogen-receptor concentration in breast cancer. The BJC is owned by Cancer Research UK, a charity dedicated to understanding the causes, prevention and treatment of cancer and to making sure that the best new treatments reach patients in the clinic as quickly as...
Hot flashes are a common problem in many women. Although hormonal treatments, some newer antidepressants, gabapentin, and clonidine have been shown to decrease hot flashes,(1-4), improved treatment options are needed to provide substantial relief without
have a shallow understanding of the cells that are there," says Associate Professor Swarbrick. "Cellular genomics is showing us that what we once thought of as one cell type is in reality a diversity of cell types, which will have a significant impact on how we tailor treatments in future....