This study has unique advantages because it can minimize the influence of other factors (such as diet, lifestyle, and environmental factors) on the gut microbiota besides mood, making it possible to screen potential psychobiotics. On the basis of the multiomics analysis, we found that the speci...
facilitating the rapid flourishing of therapeu- tic antibodies in the drug discovery field.3 Phage display technology frequently allows the creation of libraries containing up to 1011 different variants, which can be used to screen antibody clones by bio-panning.4 Despite the development of alternative...
development from procyclic to metacyclic forms and a double-stranded RNA hairpin targeting a transcript of interest for RNAi downregulation. In this screen, we did not monitor the efficacy of RNAi depletion of the targeted transcripts, and thus, if an RNAi cell line did not display a phenotype,...
To identify which cytokines were responsible for the transmission of drug resistance, we employed a cytokine antibody array to screen potential cytokines in the conditional medium of drug-resistant cells (Supplementary Figure 1c, supplementary table). As a result, CCL2 was 5.6 fold up-regulated in...
Drug development Non-small-cell lung cancer This article is cited by Mechanisms of synergistic suppression of ALK-positive lung cancer cell growth by the combination of ALK and SHP2 inhibitors M. A. Berry A. R. Bland J. C. Ashton