translation of viral‐specific RNAsflavivirus virionsviral RNA‐dependent RNA polymerasenegative‐strand RNA synthesisPublication » Positive‐Strand RNA Virus Replication in Vertebrate Hosts.doi:10.1002/9780470688618.taw0215Jo Ellen BrunnerBert L. SemlerJohn Wiley & Sons, Ltd...
Packaging of positive-strand rna virus replicon particlesPackaging of positive-strand rna virus replicon particlesPresent invention relates in general to recombination of polynucleotide, normal chain ribonucleic acid virus recombinant expression vector (psRNAV), packaging systems. The packaging system is based...
In the replication cycle of a positive-strandRNAvirus, the genomic positive stand is first copied into a negative strand genomic equivalent that serves as thetemplatefor the synthesis of more positive strands. Positive strandRNAsare needed in stoichiometric amounts to serve as mRNAs and to be...
ThePositive-strand RNA virusessection ofVirology Journalinvites submissions of research articles and reviews covering all aspects of positive-strand RNA virus biology. Basic research topics of interest include all facets of the viral life cycle from viral attachment and entry, viral RNA replication and ...
The invention generally relates to recombinant polynucleotides, positive-strand RNA virus (psRNAV) recombinant expression vectors, and packaging systems. The packaging systems are based on the express
POSITIVE-strand RNA virusesViruses are divided into seven classes on the basis of differing strategies for storing and replicating their genomes through RNA and/or DNA intermediates. Despite major differences among these classes, recent results reveal that the non-virion, intracellular RNA-replication ...
Positive-strand RNA virus genome replication is invariably associated with extensively rearranged intracellular membranes. Recent biochemical and electron microscopy analyses, including three-dimensional electron microscope tomographic imaging, have fundamentally advanced our understanding of the ultrastructure and fun...
Despite the rapid mutational change that is typical of positive-strand RNA viruses, enzymes mediating the replication and expression of virus genomes contain arrays of conserved sequence motifs. Proteins with such motifs include RNA-dependent RNA polymerase, putative RNA helicase, chymotrypsin-like and ...
A positive-strand RNA virus is a single-stranded RNA virus that is classified as positive-sensed. This means that the genome of the virus uses ribose...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your ...
(–) sgmRNA (+)5′ p2 Positive-strand synthesis p3 Protein translation p2 Figure 1 | Fundamental steps in positive-strand RNA virus replication. A linear representation of a generic positive-strand RNA viral genoNmaetuisreshRoewvniewwisth| Mthiecreonbciooldoegdy proteins represented by ...