Managed Clinical Network for Paediatric and Adolescent Rheumatology serving a childhood population of 1.03 million.MethodsCase notes were reviewed of all known current RNP positive antibody patients, presenting to paediatric rheumatology before their 16th birthday with features suggestive of a diagnosis of ...
HLA typing studies of Ro (SS-A) antibody-positive mothers of infants with NLE have shown an association with the HLA-DR3 phenotype. We report the clinical and serologic features of two infant-mother pairs who are U1RNP antibody positive and Ro (SS-A) antibody negative. HLA typing is ...
Table 1 Laboratory findings in AAV patients Items Cases ANA (+) Anti-dsDNA (+) Anti-Smith (+) Anti-DNP (+) Anti-RNP (+) Anti-SSA/Roanti-SSB/La SSA (+) SSB (+) SSA (+) SSB (−) SSA (−) SSB ( +) Anticardiolipin antibody Anti-GBM antibodies Coombs (+) C3 ...
antibody, AC-4 Anti cell-4 pattern, ENA Extractable nuclear antigen, RNP Ribonucleoprotein, Sm Smith, p-ANCA Perinuclear anti-neutrophil cytoplasmic antibodies, c-ANCA Antineutrophil cytoplasmic antibodies, dsDNA Double stranded DNA, AMA Antimitochondrial antibodies, ASMA Anti-smooth muscle antibody, AT...
RNP-electroporated T cells transduced with 1 × 104, 3 × 104, and 5 × 104genome copies/cell. ** and *** indicateP < 0.01 andP < 0.001, respectively. The center values reported are the mean and error bars represent standard deviation (SD) of at least three ...
6984Accesses 10Altmetric Metrics Abstract Tau aggregates in neurons of brain lesions is a hallmark pathology of tauopathies, including Alzheimer’s disease (AD). Recent studies suggest that the RNA-binding protein TIA1 initiates Tau aggregation by inducing the formation of stress granules (SGs) conta...
We then assessed whether anti-U1 RNP antibodies could be a prognostic factor in CTD-associated PAH with a focus on SSc-associated PAH.ResultsWe studied a total of 342 patients with CTD-associated PAH, of whom 36 (11%) were anti-U1 RNP antibody positive. Anti-U1 RNP-positive patients were...
(2009) Tunisian endemic pemphigus foliaceus is asso- ciated with the HLA-DR3 gene: anti-desmo- glein 1 antibody-positive healthy subjects bear protective alleles. Br J Dermatol 161:522-7Abida O, Zitouni M, Kallel-Sellami M et al. Tunisian endemic pemphigus foliaceus is associated with the...
Both speckled antinuclear antibody (ANA) and anti-U1 ribonucleoprotein (RNP) antibody were positive, but anti-double-stranded DNA (dsDNA) antibody and anti-Smith (Sm) antibody were negative, while complement levels were normal. Renal biopsy revealed membranous glomerulonephritis (MGN) with diffuse ...