Stromal regulation of the tumor Nicholas J. Bernard Research Highlights29 Aug 2024 Nature Immunology Volume: 25, P: 1509 TFH cell responses endure in human lymph nodes after vaccination Longitudinal sampling of human lymph nodes using fine-needle aspiration after influenza or SARS-CoV-2 vaccin...
Cell lysates were immunoprecipitated with anti-GSDMD antibody, followed by immunoblotting with anti-GSDMD and anti-Ub antibodies. IL-1β secretion in THP-1 cells was analyzed using ELISA, whereas LDH release was analyzed using LDH release assay. All results shown are representative of at least ...
Combined with the changes in the proportions of subclasses, these results indicated that although flavonols were more easily absorbed, they did not enter circulation. Together, these results characterized the preference ordering of flavonoid utilization by the giant panda. The flavonols are the highest;...
In certain media that promote only poor cell growth, avid secretion of both endogenous and heterologous proteins is observed but the metabolic basis of this regulation is not clear (26). To gain further insight in the molecular basis of how secretion can be regulated in such an apparently ...
Expression and secretion of IL-1β in human primary keratinocytes and HPV-positive cell lines.Martina, Niebler
Human papillomavirus (HPV)-positive oral squamous cell carcinoma (OSCC) is increasing worldwide with typically higher grade and stage, while better prognosis. microRNAs (miRNAs) has been shown to play a critical role in cancer, however, their role in HPV
The upregulation of both genes by P. aeruginosa can be mimicked by lipopolysaccharide (LPS) and can be blocked by the tyrosine kinase inhibitor genistein. In addition, both genes are upregulated by a variety of Gram-positive as well as Gram-negative organisms showing the same rank order of ...
axis by regulating the secretion of intestinal hormones (such as GLP-1) [33] and may also directly activate the vagus [34]. SCFAs can modulate immune cell function in the systemic circulation [35] and have direct neuroactive properties [36]. Thus, the positive benefits of SCFA-producing ...
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