Positive and negative regulation of cell proliferation through prostaglandin receptors in NIH-3T3 cells. J Cell Physiol 1996; 169(2):401-9.Watanabe T, Satoh H, Togoh M, Taniguchi S, Hashimoto Y, Kurokawa K: Positive and negative regulation of cell proliferation through prostaglandin receptors in...
T cell antigen receptor stimulation by the ligand antigen triggers multiple downstream pathways that affect CD4 + T cell function. Here authors show that activation of the downstream WNK1 kinase causes water entry into the cells, which is essential for CD4+ T cell proliferation. Joshua Biggs...
Upregulation of UBE2O promoted BC cell proliferation and EMT To explore the function of UBE2O in BC cells, western blot assays were performed with different BC cell lines to examine UBE2O expression. As shown in Fig.2a, UBE2O was obviously overexpressed in the highly metastatic cell line ...
aIt inhibits proliferation and induces apoptosis in Bcr-abl positive cell lines as well as rresh leukemic cells from Philadelphia chromosome positive chronic myeloid leukemia 它在Bcr-abl正面细胞系禁止扩散并且导致apoptosis并且rresh leukemic细胞从费城染色体正面慢性骨髓性白血病[translate]...
aIt inhibits proliferation and induces apoptosis in Bcr-abl positive cell lines as well as fresh leukemic cells from Philadelphia chromosome positive chronic myeloid leukemia 它在Bcr-abl正面细胞系禁止扩散并且导致apoptosis并且新leukemic细胞从费城染色体正面慢性骨髓性白血病 [translate] ...
The Cyclin-dependent Kinase Inhibitor p21[sup CIP/WAF] Is a Positive Regulator of Insulin-like Growth Factor I-induced Cell Proliferation in MCF-7 Human Br... The cyclin-dependent kinase inhibitor p21(CIP/WAF) is a positive regulator of insulin-like growth factor I-induced cell proliferation ...
背景与目的:代谢型谷氨酸受体4(glutamate metabotropic receptor 4,GRM4)在多种恶性肿瘤中高表达并与肿瘤患者的预后相关,但GRM4在乳腺癌中的生物学作用仍不清楚。本研究拟探讨GRM4的两种正向别构调节剂VU0364439及VU0364770对乳腺癌细胞的增殖及凋亡的影响,进而为乳腺癌的靶向治疗提供思路。方法:在体外培养的乳腺癌...
of IP3 receptors363A novel function of PI3Kg on cAMP regulation, role in arterial wall hyperplasia through modulation of smooth muscle cells proliferation364NRP1 and NRP2 play important roles in the development of neointimal hyperplasia in vivo365Azithromycin induces autophagy in aortic smooth muscle ...
Furthermore, SEM micrograph shows that TCE-AgNPs significantly inhibit the colonization and adherence of biofilm forming cells; individual cells with loss of cell wall and membrane integrity were also observed, suggesting that the biofilm architecture and EPS matrix were severely damaged. Moreover, TEM...
1.2. Transcriptional and Translational Regulation of AP-1 AP-1 TF family members are subject to strict transcriptional, translational and post-translational regulation that are cell type- and context-specific except in the case of malignancies whereby aberrant activity can drive tumour growth. At the...