Positive regulation of cell proliferation by the miR-1290-EHHADH axis in hepatocellular carcinomadoi:10.1002/cac2.12536Jinkwon LeeGyeonghwa KimTae-Su HanEunsun JungTaesang SonKwangho KimKiyoon KwonYuna RohTae Young RyuIn Hwan TaeCancer Communications...
we clarify the complicated crosstalk of Annexin A2 (ANXA2) with Glypican 1 (GPC1) and demonstrate whether combined indexes of ANXA2 and GPC1 could improve the prognostic evaluation for glioma patients. We found that ANXA2-induced glioma cell proliferation in a c-Myc-dependent ...
T cell antigen receptor stimulation by the ligand antigen triggers multiple downstream pathways that affect CD4 + T cell function. Here authors show that activation of the downstream WNK1 kinase causes water entry into the cells, which is essential for CD4+ T cell proliferation. Joshua Biggs...
aIt inhibits proliferation and induces apoptosis in Bcr-abl positive cell lines as well as rresh leukemic cells from Philadelphia chromosome positive chronic myeloid leukemia 它在Bcr-abl正面细胞系禁止扩散并且导致apoptosis并且rresh leukemic细胞从费城染色体正面慢性骨髓性白血病[translate]...
aIt inhibits proliferation and induces apoptosis in Bcr-abl positive cell lines as well as fresh leukemic cells from Philadelphia chromosome positive chronic myeloid leukemia 它在Bcr-abl正面细胞系禁止扩散并且导致apoptosis并且新leukemic细胞从费城染色体正面慢性骨髓性白血病 [translate] ...
The Cyclin-dependent Kinase Inhibitor p21CIP/WAF Is a Positive Regulator of Insulin-like Growth Factor I-induced Cell Proliferation in MCF-7 Human Breast C... Dupont J,Karas M,LeRoith D.The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor l-...
Overexpression of miR-532-5p inhibited RCC cell proliferation, while knockdown of miR-532-5p promoted cell proliferation. Mechanistic analyses indicated that miR-532-5p directly targets KRAS and NAP1L1. Interestingly, ETS1 suppressed the transcription of miR-532-5p by directly binding a special ...
Upregulation of UBE2O promoted BC cell proliferation and EMT To explore the function of UBE2O in BC cells, western blot assays were performed with different BC cell lines to examine UBE2O expression. As shown in Fig.2a, UBE2O was obviously overexpressed in the highly metastatic cell line ...
Conclusions LLL-3 reduced cell viability and induced apoptosis in K562 cells. Moreover, the observed addictive effects of co-treatment with IM and LLL-3 suggest this combination has therapeutic potential. 展开 关键词: LLL 3 STAT3 BCR ABL Imatinib ...
High expression levels of the microRNA-17~92 cluster resulted in down-regulation of BIM and TGFβRII proteins, suggesting that their targeting might mediate resistance to STAT3 knock-down in anaplastic large cell lymphoma cells. We speculate that the microRNA-17~92 cluster is involved in ...