NUCLEAR matrixINTERSTITIAL lung diseasesMUSCLE weaknessMYOSITISKey Clinical Message: Nuclear matrix protein (NXP‐2) positive amyopathic dermatomyositis (DM) may present without classic symptoms like muscle weakness, dysphagia, and edema, and mimic conditions like cutaneous lupus. Given DM's ...
(a) Explain the role of the HIV Rev protein in nuclear transport. (b) Why is this unique? What are IMViC tests and why are they valuable? Explain. Explain the purpose of immunologic tests: syphilis tests. What is PCR and why is it useful?
Background Patients with systemic autoimmune rheumatic diseases (SARD) often have a prolonged pre-clinical phase during which they are anti-nuclear antibody (ANA) but lack clinical symptoms. It has been proposed that progression from asymptomatic autoimmunity to clinical disease is accompanied by immunol...
Evaluation of anti-ds DNA antibodies in anti-nuclear antibody positive Omani patients 来自 钛学术 喜欢 0 阅读量: 28 作者:A Alnaqdy,J Al-Busaidy,B Hassan 摘要: Objective: To study the correlation between enzyme linked immunosorbent assay (ELISA) and immunofluoresencent (IF) anti-dsDNA ...
Autoantibodies are a key feature of IIM, in common with other autoimmune rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus and systemic sclerosis. Myositis-specific autoantibodies, present in 60–70% of individuals with IIM, are directed against cytoplasmic or nuclear components...
In this stuyd, 45 plasma samples from anti-HCV antibody-negative/HCV RNA-positive (window period) donors from Poland identified during nucleic acid testing (NAT) and 32 follow-up anti-HCV antibody-positive samples were tested retrospectively for HCV core antigen by Ortho Clinical Diagnostics first...
This overexpression of nuclear factor-kB-related proteins was also greater than that expected in the analysis of solely the activated B-cell-type diffuse large B-cell lymphoma cases (χ2 test: P<0.001 for all comparisons) (Table 4). Furthermore, this overexpression in age-related EBV-positive...
2c the median (Wilcoxon-Mann-Whitney-U-Test). LA lupus anticoagulant, TE thromboembolism, 2D-DIGE two-dimensional differential in-gel electrophoresis, CAPS catastrophic antiphospholipid antibody syndrome. Full size image Concentrations of leukocyte elastase inhibitor (SERPINB1) are decreased in platelets,...
It has been shown that stimulation of cells with Shh leads to rapid stabilization and nuclear translocation of Gli2FL [7]. Gli2FL protein was examined by WB in whole cell and nuclear extracts (WCE and NE, respectively) of C3H10T1/2 cells treated with 20μM SU6668 and/or Shh for 2 ...
Significance was tested by unpaired two-tailed student’s t-test (*P < 0.05, other comparisons were not significant). (c) Individual and merged brain images of the vehicle- and EPPS administered- groups stained with ThS and 6E10 or AT8 antibody (scale bars = 500 µm). wt, ...