Although the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus (SLE) has required at least a positive anti-nuclear antibody (ANA) titer (≥ 1:80), it remains challenging for clinicians to identify patients with SLE. This study aimed to develop a machine learning (ML) ap...
Tumors are composed of an evolving population of cells subjected to tissue-specific selection, which fuels tumor heterogeneity and ultimately complicates cancer driver gene identification. Here, we integrate cancer cell fraction, population recurrence, a
Sera ANA was analyzed by IF using Hep2 cells. Mann-Whitney and Fisher test were performed for statistical analysis and P<0,05 considered significant. Results All lupus-like animals presented large amounts of lipogranulomas in peritoneal cavity, and developed arthritis in both hind legs in ...
An unpaired t test was used to compare two means. One-way analysis of variance (ANOVA) was used for multiple comparisons followed by a Tukey post hoc test. *p < 0.05; **p < 0.01; ***p < 0.001. Loss of righting reflex assay in Xenopus tadpole. ...
Occult HBV infection (OBI) is defined by the persistence of HBV in the liver without serum HBsAg and HBVDNA. It represents a life-threatening event during immunosuppressive chemotherapies. An OBI occurs in approximately 18% of HBcAb + patients. Int
10.1002/hep.1840360712 Article Google Scholar Sahaf F, Tanomand A, Montazem H, Sany AA: Seroprevalence of Hepatitis C, Hepatitis B and HIV and Co-Infections among Pregnant Women: A Retrospective Study in 2006 at Malekan City, Iran. Res J Med Sci 2007, 1: 138-41. Google Scholar Luks...
target cells indicated in the figure key.dImmTAC-NYE does not lyse HLA-A2+, NY-ESO-1-/LAGE-1-negative primary human cells derived from normal tissues and expanded in culture. Purified CD8+ T cells were incubated with hepatocytes (HEP2), astrocytes (HA2), melanocytes (NHEM10), and cardiac...
Cold exposure with added LA or AA prompted a surge in PPARα levels, followed by the induction of D6D expression; addition of a PPARα antagonist or a D6D inhibitor abrogated both their expression, and reduced cell survival to control levels. We also found that the brief cold exposure ...
While larger LC3-positive structures have been seen by ourselves in autophagy-deficient HeLa cells, we also tested if this occurred in HepG2 cells. Our data showed that ATG7 + 10 knockdown decreased the number and size of LC3 structures (Supplementary Fig. 9). Thus, the phenomenon we ...
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