We will discuss further how spatial localization of intracellular feedback mechanisms can give rise to complex spatiotemporal patterns of expression in the section “Pattern formation.” Read more View chapterE
Finally, it may also be worth investi- gating the behaviour of these modified VP16 elements in insect control systems that do not rely on tTAV positive feedback [7, 14, 15]. There are several reasons why it is difficult to categor- ically refute the proposed mechanisms of tTAV ...
Among these mechanisms, positive feedback loops and signal crosstalk are particularly notable, underscoring the role of STAT3 as a key node in the convergence of various signaling pathways. Targeting STAT3, either by indirectly inhibiting it through blocking upstream signaling pathways or directly suppres...
Understanding Positive Feedback: Positive feedback systems are the enhancement of the action of a product of a physiological process to amplify the effect on the system. Positive feedback systems are cyclic processes that amplifies the body's respo...
feedback and the continental shelves are finite, we impose bounds on the feedback term in our model. For this purpose, we propose the use of a simple sigmoid function (arctan) that tends towards constant values at low and high alkalinity:I=I0(1+γS(A)),withS(A)=2πtan−1(...
A single gene with only positive transcriptional feedback does not produce oscillations. Here, we demonstrate that this single-gene network in conjunction with a simple negative interaction can also easily produce rhythms. We examine a model comprised of two well-differentiated parts. The first is ...
(for example, WRF-CAMx) or reduced-form (for example, CHEER-AIR) regional air quality models, the underlying self-reinforcing feedback mechanisms and the amplifying air quality and human health benefits due to weakened aerosol–meteorology interactions under China’s carbon neutral target have not ...
It is unclear what may be the mechanisms underlying GSK3β regulation of PP1 in the nucleus. The possibilities include (i) existence of a nuclear GSK3β targets /I2/PP1 complex that CREB Ser133 and/or (ii) a potential stimulatory effect of GSK3β-mediated phosphorylation of CREB Ser129...
One effective route to increasing well-being is through the pursuit of activities which suit a person’s personality strengths (i.e., person-activity
feedback may cause a considerable boost in warming. 1. Introduction [2] The direct effects of CO 2 and other greenhouse gases on earth temperature are relatively well understood. However, estimation of the overall effect of anthropogenic