The presence of Molecule B increases the production of Molecule B in this example of a positive feedback loop. Examples of Positive Feedback Positive feedback can also be very beneficial to an organism.Positive vs Negative Feedback Lesson Summary Register to view this lesson Are you a student ...
In addition, p62 is a stress-inducible protein whose expression is regulated by Nrf2 (ref. 10), and p62 overproduction is sufficient for phosphorylation of p62 to inactivate Keap1 (ref. 9), resulting in a positive-feedback loop that accelerates Nrf2 activation. Thus, chronic inflammation in ...
Today, I came across an interview with Jerry Seinfield that left an impression on me. One paragraph in particular stood out: If you’re efficient, you’re doing it the wrong way. The right way is the hard way. The show was successful because I micromanaged it—every word, every line, ...
Next, we examined proliferation of HCC cells expressing wild-type or mutant p62. Expression of wild-type and S351E significantly promoted proliferation in several HCC cell lines, although not in Huh1; S351E-expressing cells grew more rapidly than wild-type p62-expressing cells (Fig. 5b). In...