Factor V Leiden and sepsis: Proof positive or phenomenology?EBSCO_AspCritical Care Medicine
Inserts were coated with growth-factor reduced matrigel (Corning) diluted in mixed medium to a concentration of 0.5 mg/ml protein. Coated inserts were placed in bottom wells with CM and 5 × 105 splenocytes were plated in the inserts in the presence or absence of neutralizing ...
Spontaneous coronary artery dissection (SCAD) is an extremely uncommon condition that can lead to fatal acute myocardial infarction. There have been very few case reports of SCAD in patients with systemic lupus erythematosus (SLE) and even fewer in association with antiphospholipid antibodies – mainly...
Rheumatoid factor PPV: Positive predictive value NPV: Negative predictive value pSS: Primary Sjögren’s syndrome References van Venrooij WJ, van Beers JJ, Pruijn GJ. Anti-CCP antibody, a marker for the early detection of rheumatoid arthritis. Ann N Y Acad Sci. 2008;1143:268–85. Ar...
There is also the factor of the leftist bias of the press, academia, and the literati. In both Britain and American, one would expect the weight of conservative pluralities to tell in politics. Sometimes it does, as in the three elections won byPresident Reagan(who, really, was responsible...
one of the most significant forms of which is factor V Leiden deficiency; women with this specific type of thrombophilia are 35 times more at risk of developing venous thromboembolism over other baseline risks. Women who don’t have thrombophilias but are over 45 years old, smoke more than...
and inhibitors of STAT3 have been developed as novel treatment strategies for cancer63,64. Additionally, STAT3 induces the expression of hypoxia-inducible factor-1α (HIF-1α), which is another crucial mediator of angiogenesis. The simultaneous binding of both STAT3 and HIF-1α to the VEGF-A ...
Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products. Mol Cell Biol 1991; 11: 4854–4862. 25. Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, Mundiger T et al. The simultaneous loss of Arx and Pax4 ...
Results from Cohorts A and B of the Phase 2 portion of the study are being presented in two poster presentations, titled “Safety, Efficacy, and Patient-Reported Outcomes with Vimseltinib in Patients with Tenosynovial Giant Cell Tumor Who Received No Prior Anti-Colony-Stimulat...
LBP zeigt N-terminale Sequenz-Homologie mit dem LPS-bindenden Protein, genannt BPI (bactericidal permeability-increasing factor) (Tobias et al., supra, 1988). BPI wird in spezifischen PMN-Körnchen gespeichert (Weiss et al., Blood, 69:652-659, 1987) und tötet Gram-negative Bakterien...