The residual liquid in patients' immunoglobulin preparations showed positive ANAs with a high titer of AC-19 (1:640), a low titer of the nuclear fine speckled pattern (AC-4, 1:80), positive AMA-M2, and positive anti-SSA. ANA-related autoantibodies were tested in 16 batches of ...
titer,but even a high-titer ANA is not proof of an underlying connective tissue disease.Therefore, not surprisingly,ANA testing is frequently positive in patients with fibromyalgia.Consequently, the ANA alone is not a reliable tool for discriminating non-inflammatory conditions from autoimmune diseases...
Only one (16%) patient exhibited positive ANA; however, up to four (66%) patients showed positive anti-Ro52 antibody results. 3.3. Treatment data All patients received a high dose of corticosteroids combined with immunosuppressive drugs for ILD. Among RP-ILD patients, three cases were ...
Molar carbon (rC,a) and nitrogen (rN,b) assimilation rates of PCC6803 under different steady state conditions. Cells were grown with ammonium (striped bars) or nitrate (white bars) as N source under LLHC (low light high carbon), HLHC (high light high carbon), and HLLC (high light low...
The addition of PE to immunosuppressive drugs is expected to improve the poor outcome in anti-MDA5 Ab-positive patients with RP-ILD, although the significance of decreasing anti-MDA5 antibody titer by PE has not been determined [31]. Currently, there have been a limited number of case ...
Two previously described sisters with folic acid nondependent formiminoglutamic aciduria also excrete abnormally high amounts of hydantoin-5-propionic acid ( H P A ) . HPA was identified by gas chromatography-mass spectrometry as the N,Nf-bis-trimethyl- silyl methyl ester- and N,O-permethyl ...
Abbreviations SLE: Systemic lupus erythematosus; JPM: Juvenile polymyositis; MCTD: Mixed connective tissue disease; ANA: Anti-nuclear antibody; EMG: Electromyogra‑ phy; MRI: Magnetic resonance image; RF: Rheumatoid factor; ILD: Interstitial lung disease; HRCT: High-resolution computed ...
. The maximum observed ADA titer in obinutuzumab-pretreated patients was 1:270, while ADA titers were in general higher in patients who were not pretreated with obinutuzumab, with a maximal observed titer of 1:196,830 (study S1). In the obinutuzumab-pretreated population, cibisatamab exposure ...
with referral instructions, the majority of patients we interviewed appeared to take HAT seriously, including their own risk from it, particularly when receiving a positive result from a HAT RDT. They also largely trusted the effectiveness of tests positioned at high level facilities. So how should...
burgdorferi, repeated vaccine administration is required to maintain the minimal protective titer. The high OspA and OspC antibody titers induced by Subunit-AC allow for antibody-mediated killing to occur in both the tick and mammal with the potential for an OspC-induced anamnestic response (Hatke...