Table 1 Laboratory findings in AAV patients Items Cases ANA (+) Anti-dsDNA (+) Anti-Smith (+) Anti-DNP (+) Anti-RNP (+) Anti-SSA/Roanti-SSB/La SSA (+) SSB (+) SSA (+) SSB (−) SSA (−) SSB ( +) Anticardiolipin antibody Anti-GBM antibodies Coombs (+) C3 ...
The ANA patterns were most commonly nuclear granular and nuclear homogeneous types (50%), and the anti-Ro-52 antibody was positive in 5 cases. Additionally, ESR, CRP, and serum ferritin were elevated in 6, 3, and 8 cases, respectively. Moreover, reduced T lymphocyte count and increased ...
electromyography and muscle biopsy were performed and the patients were given the related treatments after confirmed diagnosis.The anti-Jo-1 and anti-Ro-52 antibodies were strongly positive in the myositis antibody spectrum of the two patients;the lung CT results showed interstitial pheumonia;the ...
regarding Rab3s (A,B,C,and D),it is difficult to formulate a coher- e nt hypo thesis a bo ut the functio ns o f these prote ins in me mbrane fus io n.Ra b3A has be e n cla ime d to mainta in t he supply o f ves icles ...
anti‐SSA antibodyclinical characteristicsmisdiagnosisIn China, the incidence of autoimmune diseases is gradually increasing. To decrease the misdiagnosis rate of autoimmune diseases, we conducted an epidemiological investigation about the presence of antinuclear antibody (ANA) in healthy populations and ...
Laboratory testing revealed low serum complement levels and positive titers for ANA, SSA, and dsDNA; AQP4-IgG was positive at a titer of > 1:100,000. Myelin oligodendrocyte glycoprotein (MOG) and antiphospholipid antibodies were negative. Skin biopsy demonstrated leukocytoclastic vasculitis. MRI ...
The residual liquid in patients' immunoglobulin preparations showed positive ANAs with a high titer of AC-19 (1:640), a low titer of the nuclear fine speckled pattern (AC-4, 1:80), positive AMA-M2, and positive anti-SSA. ANA-related autoantibodies were tested in 16 batches of ...
Objectives To clarify clinical and immunological features of ACA-positive SjS and their association with autoantibodies. Methods Patients with discrete-speckled pattern in anti-nuclear antibody (ANA) test and/or positive ACA, who visited to our service between 2012 and 2015, were enrolled. Clinical ...
There is a great deal of evidences that a link may exist between psoriasis and autoimmunity. In this study, thirty-six patients with psoriasis vulgaris and twenty healthy controls were screened for antinuclear antibody (ANA), anti-ds-DNA antibodies, anti-SSA (anti-Ro), anti-SSB (anti-La),...
There is a great deal of evidences that a link may exist between psoriasis and autoimmunity. In this study, thirty-six patients with psoriasis vulgaris and twenty healthy controls were screened for antinuclear antibody (ANA), anti-ds-DNA antibodies, anti-SSA (anti-Ro), anti-SSB (anti-La),...