MCI with a high PRS showed a significantly increased conversion to AD in APOEε4 noncarriers with a hazard rate of 2.22. In addition, we also developed a PRS model adjusted for LD and observed similar results. Conclusions We showed that the AD PRS is useful in the Japanese population, ...
For instance, a wearable sensor that detects when aging workers perform their task in a way that is likely to cause injury would alert a worker to the potential hazard and give them time to adjust their physical approach to their task. A system that diagnoses mild cognitive impairment at ...
Injury events: utility of self-report in retrospective identification in the USA Journal of Epidemiology and Community Health (1994) BrowningS.R.et al. Agricultural injuries among older Kentucky farmers: the farm family health and hazard surveillance study ...
Five SNPs on 19p13 were associated with breast cancer risk (Ptrend = 2.3 × 10−9 to Ptrend = 3.9 × 10−7), two of which showed independent associations (rs8170, hazard ratio (HR) = 1.26, 95% CI 1.17–1.35; rs2363956 HR = 0.84, 95% CI 0.80–0.89). Genotyping these SNPs ...
Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA * Author to whom correspondence should be addressed. † Zhengqiu Zhou and Connor J. Kinslow contributed equally to this manuscript and are co-first authors. J. Clin. Med.2019,8(2), 246;https://doi.org/10.3390/jcm802...