Here, we discuss sampling designs, methods for determining data quality (bias and precision), and methods for detecting change, and we provide some examples of results from the ongoing community-based data collection program. We also report on (1) the design and implementation of scientifically ...
Based on these examples, we suggest that a theory crisis can lead to three types of questionable research practices, QRPs (see Fig.1). These three “new” extensions of QRPs are counterparts to well-known issues of empirical studies: HARKing (hypothesizing after results are known),p-hacking...
In the context of flow intermittency, we illustrate the trait state complex through two examples of traits: body size and wing size. Body size plays a key role in an organism’s survival strategy, as species with smaller body sizes are better adapted to avoid flow intermittency by easily ...
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy characterized by varied responses to treatment and prognoses. Understanding the metabolic characteristics driving DLBCL progression is crucial for developing personalized therapies. This
C The expression levels of MDM4 in different cell lines using the Cancer Cell Line Encyclopedia database. D Histograms of the MDM4 protein expression levels and examples of Immunohistochemistry images from the Human Protein Atlas. E Representative images from immunohistochemical ...
HRP-labeled goat anti-rabbit and anti-mouse IgG are examples of secondary antibodies (Jackson, USA). GLUT1 (Cat No. SC-377228), GPI (Cat No. SC-377228) were from Santa Cruz Biotechnology (USA). Glucose consumption and lactic acid measurement Cell culture supernatants were collected and ...
a, RNA velocity and pseudotime analysis using the CellRank39 method, applied to the CRC epithelial scRNA-seq data. b, UMAP visualization displays patient-based clusters (left) and scatterplot between MYC targets and PRC targets ssGSEA scores (right) with cells annotated with pseudotime. P valu...
Generating data from a directed network Full size image Types of networks Examples of the generated directed acyclic graphs that are used as ground truth in the simulations. Full size image Results Figures5and6display the result of the simulation study. Figure5shows a homogeneous picture of correla...
(SeeTable 1). The interviews were conducted between September 2018 and September 2019. Through the interviews, we investigated the different risks which materialized in the life cycle of infrastructure megaprojects. We also asked respondents about examples of such risks from their experience and sought...
Representative examples of both positive (C, D, and E) and negative (F) MT-3 staining of the tumors are shown in Figure 1. The MT-3 staining was diffuse and localized to the cytoplasm in all MT-3 positive tumors. Repeatability was examined, and the MT-3 staining characteristics were ...