Omega-3 polyunsaturated fatty acids (PUFA), in particular the marine-derived forms eicosapentaenoic acid and docosahexaenoic acid, have been touted as natural, multipotent treatments for a wide variety of disease conditions. Interest in using these PUFA (found in marine algae and fatty cold water ...
Additionally, DHA could largely inhibit TGF尾1-stimulated Akt but not S6 or Smad3 phosphorylation at a time dependent manner. To decipher the role for n-3 PUFAs in protecting against kidney fibrosis, fat-1 transgenic mice were operated with unilateral ureter obstruction (UUO). Compared to the...
Because modern diets are relatively deficient in this special type of fat, there is a great potential for improving many aspects of health by adding it to the diet (Lands, 2003). For example, omega-3 fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are ...
(1992)studied the effect of omega-3 PUFA on cardiac performance in marmoset monkeys and showed that specified dietary treatment was beneficial and the performance of animal's heart improved.McLennan (1993)stated that the replacement of saturated animal fat in the diet with omega-3 rich fish oil...
Generic name: omega-3 polyunsaturated fatty acids [ oh-MAY-ga-3 POL-ee-un-SAT-yoo-ray-ted-FAT-ee-AS-ids ] Brand names: Animi-3 with Vitamin D, BP Vit 3, Cardio Omega Benefits, Dry Eye Omega Benefits, EPA Fish Oil, ... show all 77 brands Dosage forms: oral capsule (-; 1000...
Omega-3 polyunsaturated fatty acids are known to have therapeutic potential in several neurological and psychiatric disorders. However, the molecular mecha... N Blondeau,C Nguemeni,DN Debruyne,... - 《Neuropsychopharmacology Official Publication of the American College of Neuropsychopharmacology》 被引...
Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids. Nature. 2004;427(6974):504. CAS PubMed Google Scholar Kang JX. Fat-1 transgenic mice: a new model for omega-3 research. Prostaglandins Leukot Essent Fatty Acids. 2007;77(5–6):263–7. CAS PubMed Central PubMed Google ...
The OmegAD study also found similar results in which benefits of n–3 PUFAs (1.7 g DHA and 0.6 g EPA/d for 6 mo) were observed in very mild AD but not in advanced AD (99). This suggests that n–3 PUFA supplementation might not be beneficial in advanced stages of disease in which...
The β cell population is not affected by dietary fat in non-infected mice, but the fish oil enrichment results in the highest percentage of β cells in infected mice [33]. Furthermore, fortifying the diet with n-3 PUFA from fish oil (5%) significantly increased serum IgG concentration and...
These results indicated that omega-3 PUFAs, but not AA, increased neuronal differentiation. Omega-3 PUFAs enhanced neurogenesis in the adult rat hippocampus [5], embryonic rat brain [6], lobster brain [7], and in fat-1 transgenic mice [8]. Kan et al. [19] reported that treatment with...