英文名字 K48-linked Polyubiquitin Antibody 供应商 Biogradetech 产品货号 BGT-ANT-36566 产品报价 ￥询价/50ug ￥100ug ￥1mg 产品说明书 点击查看 购买方式 国外全部现货。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系,本公司所有产品仅供科研使用,不用于临床诊断。
The crystal structure of MIU2 in complex with K48 linked polyubiquitin chains reveals that MIU2 on its own binds to all three Ub moieties in an open conformation that can only be accommodated by K48-linked triUb. The weak Ub binder MIU1 increases overall affinity of the tMIU for polyUb...
Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activat...
A20, also known asTNFAIP3(TNFα-induced protein 3), is anOTUdomain-containingDUBthat preferentiallyhydrolyzesK63-linked polyubiquitination. This enzyme also possessesE3 ubiquitin ligaseactivity mediating K48-linked polyubiquitination. In particular, A20 acts as a ubiquitin-editing enzyme ofRIPK1that rep...
抗K48-LINKED POLYUBIQUITIN 抗体 (ABS1497)(一抗) CBNumber: CB215175742 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商2 抗K48-LINKED POLYUBIQUITIN 抗体 (ABS1497)(一抗)化学性质 安全信息 抗K48-LINKED POLYUBIQUITIN 抗体 (ABS1497)(一抗)性质、用途与生产工艺 ...
中文名称:抗体:K48-LINKED POLYUBIQUITIN ANTIBODY (SAA0329) RHC59302 中文同义词:抗体:K48-LINKED POLYUBIQUITIN ANTIBODY (SAA0329) RHC59302 英文名称:K48-linked Polyubiquitin 英文同义词:K48-linked Polyubiquitin CAS号: 分子式: 分子量:0 EINECS号: ...
Modification of proteins by addition of K63-linked polyubiquitin chains is implicated in a variety of cellular events, including DNA repair, signal transduction and receptor endocytosis. A monoclonal antibody (mAb) has been generated that specifically recognizes K63-linked polyubiquitin chains, but not...
Upon addition of Rpn1214–355, the NMR spectra of K48-linked Ub2 with the distal (lysine-accepting) Ub 15N-enriched (15N-dK48-Ub2) displayed significant signal shifts and attenuations—characteristic indicators of binding (Fig. S3A). These signal shifts, quantified on a per-residue basis ...
The finding that NEMO can bind to K63-linked, but not K48- linked, polyuqituitin chain is surprising, as the CC2 and LZ motifs of NEMO do not contain any known ubiquitin-binding domain. As is the case with many novel discoveries, more exciting or even confusing questions were raised ...
Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine. Chem. Commun. 46, 7199–7201 (2010). Article CAS Google Scholar Kumar, K. S. A., Spasser, L., Erlich, L. A., Bavikar, S. N. & Brik, A. Total chemical synthesis of di-ubiquitin chains. Angew....