产品名称:RNA Polymerase III Inhibitor 别名: N-[1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl)]-2-chlorobenzenesulfonamide CAS号: 577784-91-9 描述: RNA Polymerase III Inhibitor is a cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory ...
Section 37 DNA polymerase I & III DNA聚合酶国高生物Stephanie张 立即播放 打开App,流畅又高清100+个相关视频 更多163 -- 0:34 App Section 39 Topoisomerase (Gyrase) 拓扑异构酶 679 1 2:38 App Section 49 Gene mutation 基因突变2(缺失,插入,移码突变) 90 -- 0:31 App Section 31 RNA 174 2 ...
RNA polymerase III (Pol III) transcribes noncoding RNA, including transfer RNA (tRNA), and is commonly targeted during cancer and viral infection. We find that Herpes Simplex Virus-1 (HSV-1) stimulates tRNA expression 10-fold. Perturbation of host tRNA synthesis requires nuclear viral entry, ...
RNA polymerase III (Pol III) transcription initiation requires the action of the transcription factor IIIB (TFIIIB) and is highly regulated. Here, we determine the structures of Pol III pre-initiation complexes (PICs) using single particle cryo-electron microscopy (cryo-EM). We observe stable Pol...
RNA polymerase (Pol) III transcribes essential non-coding RNAs, including the entire pool of transfer RNAs, the 5S ribosomal RNA and the U6 spliceosomal RNA, and is often deregulated in cancer cells. The initiation of gene transcription by Pol III requires the activity of the transcription facto...
Assembled RNA polymerase III (Pol III) complexes exert local effects on chromatin processes, including influencing transcription of neighboring RNA polymerase II (Pol II) transcribed genes. These properties have been designated as `extra-transcriptional'
Epstein-Barr Virus (EBV)-encoded RNAs (EBERs) are non-polyadenylated RNA molecules transcribed from the EBV genome by RNA polymerase III (pol III). EBERs are the most abundant viral latent gene products, although the precise mechanisms by which EBV is able to achieve such high levels of EBE...
图1. 分别用翌圣Bst Plus DNA Polymerase(橙色)和竞品N(灰色)、竞品T(蓝色)的Bst酶进行RT-LAMP反应,使用各自制造商推荐的最佳方案,扩增新 冠病毒。结果表明,翌圣Bst Plus DNA Polymerase始终能比竞品更快达到阈值,扩增速率更快。2、高dUTP耐受性 使用翌圣Bst Plus DNA Polymerase进行RT-LAMP反应,扩增新 冠病毒...
This is particularly challenging when measuring the activity of RNA polymerase III (Pol III), which transcribes growth-promoting small RNAs. To address this issue, we developed Corn, a genetically encoded fluorescent RNA reporter suitable for quantifying RNA transcription in cells. Corn binds and ...
and of the RNAP III at the promoter. This exceptional stability provides a stable anchor point for RNAP III at the promoter, which supports transcription of the short U6, tRNA and 5S rRNAs. Moreover, we demonstrate that the DNA origami force clamp is a powerful tool to study the force ...