Synonyms Autosomal dominant polycystic kidney disease; ADPKD ; Autosomal recessive polycystic kidney disease; ARP KD Definition and Characteristics ADPKD refers to enlarged cystic kidneys during adulthood leading to hypertension and progressive renal failure. Cysts also occur in the liver and the pancreas....
Polycystic kidney disease: ADPKD and ARPKD. In: Geary DF, Schaefer F (eds). Comprehensive Pediatric Nephrology. Philadelphia: Mosby Elsevier, 2008, 155-178Bergmann C and Zerres K. Polycystic Kidney Disease: ADPKD and ARPKD, in Comprehensive Pediatric Nephrology, D.F. Geary and F. Schaefer, ...
The disease often leads to chronic renal failure and may result in total loss of kidney function, known as end stage renal disease (ESRD), which requires some form of renal replacement therapy (e.g. dialysis). Autosomal recessive polycystic kidney disease (ARPKD) is much rarer than ADPKD ...
Scolari7, Claudia Izzi7, Alberto Edefonti8, Susanna Negrisolo9, Elisa Benetti10, Maria Teresa Sciarrone Alibrandi11, Paolo Manunta11, Alessandra Boletta3 & Maurizio Ferrari1,2,12 Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney ...
Polycystic kidney disease (PKD) is a heritable disorder with diffuse cystic involvement of both kidneys without other dysplastic elements. The term PKD is generally used to describe two genetically distinct syndromes: Autosomal dominant polycystic kidney disease (ADPKD) Saccular, epithelial-lined, fluid...
Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are important inherited kidney diseases with distinct clinical features and genetics. Although these diseases have classically been considered "adult" (ADPKD) or "infantile/pediatric" (ARPKD), it...
Polycystic kidney disease can be of two types : Autosomal dominant PKD (ADPKD) Autosomal dominant inheritance means that the abnormal gene from even one parent is sufficient to inherit the disease. ADPKD is the most common inherited form, present in 90% cases of PKD. It can be asymptomatic fo...
ADPKD ○ Positive family history ○ Abdominal andflank pain ○ Gross or microscopichematuria ○ Urinary tract infections (UTIs) ○ Kidney stones ○ Hypertension ○ Renal cystsmay be discovered, even onprenatal ultrasound. • ARPKD ○ Parents unaffected ...
摘要: Polycystic kidney disease (PKD) is a potentially life-threatening disorder that affects both adult and pediatric patients. PKD can be either inherited as a dominant (ADPKD) or a recessive trait (ARPKD关键词: Animal models Persistent estrus Polycystic ovary Polycystic ovary syndrome Chronic an...
and the Japan Kidney Association, a non-profit organization, have concluded a comprehensive agreement to collaborate in Japan on raising the level of disease awareness and medical care for autosomal dominant polycystic kidney disease (ADPKD), a rare and incurable disease of the kidney. Otsuka Pharmac...