Antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp330. 靶标信息 Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that ...
Antibody detects endogenous levels of fragment of activated Caspase-1 resulting from cleavage adjacent to Ala317. 靶标信息 Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala. This cleavage causes the release of the mature cytokine which is involved...
Subcellular Locations:CytoplasmSwiss Prot:P42574 保存:Store at -20°C. Avoid freeze / thaw cycles.别名:CPP32;CPP32B;SCA-1;Caspase 3;SREBP cleavage activity 1;Cysteine protease CPP32 产品编号:K003262P储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. ...
中文名称:Caspase-3 Rabbit Polyclonal Antibody英文名称:Caspase-3 Rabbit Polyclonal Antibody 有效期:一年产品类别:凋亡与自噬 Regulation of Apoptosis 产品编号产品名称产品包装产品价格 AF0081Caspase-3 Rabbit Polyclonal Antibody50μl416.00元 来源用途交叉反应性分子量 ...
背景资料:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppre...
All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a tetramer to form the active enzyme. Caspase-1/ICE (IL-1b converting enzyme) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates ...
and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that enc...
别名: CPP32;CPP32B;SCA-1;Caspase 3;SREBP cleavage activity 1;Cysteine protease CPP32 产品编号: K002389P 储存液: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 纯化方法: Affinity purification 蛋白分子量: 32kDa 交叉反应: Human Mouse Rat 克隆类型: Polyclonal Antibody 免疫原: Reco...
cleavage of cellular substrates that ultimately lead to cell death. Caspase 7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3...
The caspase-3-mediated cleavage and activation of ROCK I induces phosphorylation of MLC and membrane blebbing, one of the first events in the execution phase of apoptosis. 仅用于科研。不用于诊断过程。未经明确授权不得转售。相关产品 蛋白质免疫印迹 Secondary Antibodies 同型对照 WB内参抗体 蛋白...