Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).,function:Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.,online information:Caspase-9 entry,PTM:Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and ...
XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells. The MW of XIAP is 45-56 kDa. Protocols Product ...
Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter ...
(BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-...
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of cas... PB Catalog Number: 被引量: 0发表: 0年 Polyclonal Anti- WASP PicobandTM Antibody E3 SUMO-protein ligase PIAS4, also known as protein inhibitor of activated STAT protein 4 (...
lymphoma model and activated (by phospho-Akt staining) and/or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Inhibitor: RX-0201. Substrates include tuberin, Bad, Forkhead transcription factors, caspase-9, and glycogen synthase ...
December 28, 2022Djou0 Comments Promoted Lab recombinants Our used TESTs in Pubmed. Read more Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.Mono(2-ethylhexyl) phthalate accelerates early fo...
In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with caspase-9, thereby allowing the processing and activation of the caspase. 包装清单: 产品编号 产品名称 包装 AF5333 XIAP Rabbit Polyclonal Antibody (KO Validated) 50μl AZ050 Western一抗...
(mTOR) in a rapamycin-insensitive complex with rictor and Sin1. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including Bad, forkhead transcription factors, c-Raf, and caspase-9. PTEN phosphatase is a major negative regulator of the ...
Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. 仅用于科研。不用于诊断过程。未经明确授权不得转售。篇参考文献 (0) 您是否在文献中引用过该产品?请点击下方按钮邮件告知我们。 引用该产品 生物信息学 蛋白别名: acidic (leucine-rich) ...